Dual μ-opioid receptor and norepinephrine reuptake mechanisms contribute to dezocine- and tapentadol-induced mechanical antiallodynia in cancer pain.
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DOI: 10.1016/j.ejphar.2020.173062
Abstract: Dezocine is an opioid analgesic widely used in China, occupying over 45% of the domestic market of opioid analgesics. We have recently demonstrated that dezocine produced mechanical antiallodynia and thermal antihyperalgesia through spinal μ-opioid receptor… read more here.
Keywords: dezocine tapentadol; opioid receptor; mechanical antiallodynia;