Cellular protective effect of novel dimeric ferulamide derivatives against UVA and 1O2 and its structural mechanism
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Industrial and Engineering Chemistry"
DOI: 10.1016/j.jiec.2017.04.021
Abstract: Abstract N , N ′-Diferuloyl-putrescine (DFP) containing ferulamide moiety has skin whitening and antioxidative activities. In this study, we synthesized DFP (n = 4), DFP-1 (n = 3) and DFP-2 (n = 2) with different diamide linkage chain lengths connecting dimeric… read more here.
Keywords: dimeric ferulamide; protective effect; effect novel; cellular protective ... See more keywords
A new fluorescent probe for sensing Al3+ ions in the solution phase and CH3COO− in the solid state with aggregation induced emission (AIE) activity
Sign Up to like & getrecommendations! Published in 2023 at "RSC Advances"
DOI: 10.1039/d2ra06978d
Abstract: An AIE (aggregation induced emission) active probe DFP–AMQ was designed and synthesized as a hexa-coordinated N2O donor chelator for the selective sensing of Al3+ colorimetrically as well as fluorimetrically with a 27-fold fluorescence enhancement for… read more here.
Keywords: aggregation; al3 ions; dfp amq; dfp ... See more keywords
Iron chelation promotes mitophagy through SENP3-mediated deSUMOylation of FIS1
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2046898
Abstract: ABSTRACT The selective clearance of mitochondria by mitophagy is an important quality control mechanism for maintaining mitochondrial and cellular health. Iron chelation, for example by the compound deferiprone (DFP), leads to a specific form of… read more here.
Keywords: senp3; fis1; dfp; iron chelation ... See more keywords
Neuroprotective Effects of AEOL10150 in a Rat Organophosphate Model
Sign Up to like & getrecommendations! Published in 2018 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfx283
Abstract: Prolonged seizure activity or status epilepticus (SE) is one of the most critical manifestations of organophosphate exposure. Previous studies in our laboratory have demonstrated that oxidative stress is a critical mediator of SE-induced neuronal injury.… read more here.
Keywords: neuroprotective effects; treatment; stress; dfp ... See more keywords
Prolonged (post‐thaw) shelf life of −80°C frozen AB apheresis plasma
Sign Up to like & getrecommendations! Published in 2020 at "Transfusion"
DOI: 10.1111/trf.15963
Abstract: ABSTRACT BACKGROUND Early plasma transfusion is important in the treatment of patients with major hemorrhage. Prolonged shelf life of AB type frozen −80°C and cold‐stored (4°C) deep frozen plasma (DFP) will improve strategic stock management,… read more here.
Keywords: prolonged post; plasma; shelf life; blood ... See more keywords
Abstract 848: The Iron Chelator Deferiprone Clears Hemorrhagic Byproducts Following Acute Myocardial Infarction in a Swine Model of Ischemia-Reperfusion
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.848
Abstract: Current treatments for myocardial infarction (MI) aim to remove the vascular occlusion and reperfuse the infarcted tissue. While reperfusion can salvage myocardium, it can also increase damage to the unsalvageable tissue, one mechanism of which… read more here.
Keywords: treatment; reperfusion; post; iron ... See more keywords
Everyone needs robust analytics: Integrating medical ontologies into the Dana-Farber Pathways.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.27_suppl.304
Abstract: 304 Background: The majority of clinical data is unstructured. Medical ontologies standardize the language used to communicate diagnoses, symptoms, and procedures used in healthcare. Incorporating medical ontologies into the Dana-Farber Pathways (DFP) provides structure and… read more here.
Keywords: dana farber; ontology; medical ontologies; dfp ... See more keywords
Delayed facial palsy after microvascular decompression for hemifacial spasm: friend or foe?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of neurosurgery"
DOI: 10.3171/2017.3.jns162869
Abstract: OBJECTIVE The authors investigated the incidence, clinical course, and predisposing factors associated with delayed facial palsy (DFP) following microvascular decompression (MVD). METHODS The authors reviewed the records of 310 patients (311 cases) who were followed… read more here.
Keywords: delayed facial; microvascular decompression; facial palsy; hemifacial spasm ... See more keywords
Long-term safety of deferiprone treatment in children from the Mediterranean region with beta-thalassemia major: the DEEP-3 multi-center observational safety study
Sign Up to like & getrecommendations! Published in 2018 at "Haematologica"
DOI: 10.3324/haematol.2017.176065
Abstract: Early iron chelation therapy is fundamental in the treatment of b-thalassemia major (b-TM) to avoid the adverse effects of chronic transfusional iron overload. Deferiprone (DFP) was the first oral iron chelator, but remains second line… read more here.
Keywords: deferiprone; safety; thalassemia major; study ... See more keywords
Dragon Fruit Peel Waste (Hylocereus undatus) as a Potential Ingredient for Reducing Lipid Peroxidation, Dietary Advanced Glycation End Products, and Starch Digestibility in Cookies
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12051002
Abstract: Excessive consumption of cookies has been linked to harmful health outcomes owing to the presence of refined carbohydrates and heat-induced toxicants including end products of lipid peroxidation and dietary advanced glycation end products (dAGEs). To… read more here.
Keywords: lipid peroxidation; end products; dietary advanced; peroxidation dietary ... See more keywords