Evaluation of soluble carbonic anhydrase IX as predictive marker for efficacy of bevacizumab: A biomarker analysis from the geparquinto phase III neoadjuvant breast cancer trial
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32163
Abstract: We analyzed the predictive potential of pretreatment soluble carbonic anhydrase IX levels (sCAIX) for the efficacy of bevacizumab in the phase III neoadjuvant GeparQuinto trial. sCAIX was determined by enzyme‐linked immunosorbent assay (ELISA). Correlations between… read more here.
Keywords: soluble carbonic; carbonic anhydrase; bevacizumab; efficacy bevacizumab ... See more keywords
The prognostic and clinicopathological value of tumor-associated macrophages in patients with colorectal cancer: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-020-03686-9
Abstract: There is a growing literature on the significance of tumor-associated macrophages (TAMs) in colorectal cancer (CRC). However, the role of TAMs in predicting the prognosis of CRC remains controversial. The current study aims to determine… read more here.
Keywords: tumor associated; density; dfs; cancer ... See more keywords
Inhibition of autophagy sensitizes lignan-induced endoplasmic reticulum stress-mediated cell death.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.03.081
Abstract: Relationship between autophagy and endoplasmic reticulum (ER) stress and their application to treat cancer have been actively studied these days. Recently, a lignan [(-)-(2R, 3R)-1,4-O-diferuloylsecoisolariciresinol, DFS] from Alnus japonica has been found to reduce the… read more here.
Keywords: cancer; dfs; endoplasmic reticulum; reticulum stress ... See more keywords
Utility of the CPS + EG scoring system in triple-negative breast cancer treated with neoadjuvant chemotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of cancer"
DOI: 10.1016/j.ejca.2021.05.027
Abstract: BACKGROUND Pathological complete response (pCR) after neoadjuvant chemotherapy (NACT) is associated with superior survival. This association is strongest in triple-negative breast cancer (TNBC). The CPS + EG system, based on pre-treatment clinical (CS) and post-treatment pathological stage… read more here.
Keywords: negative breast; year; cps; breast cancer ... See more keywords
Glucose transporter 3 gene variant is associated with survival outcome of patients with non-small cell lung cancer after surgical resection.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.04.013
Abstract: This study was conducted to explore whether polymorphisms of glucose transporter 3 (GLUT3) gene affect the prognosis of patients with non-small cell lung cancer (NSCLC) after surgical resection. Four single nucleotide polymorphisms (SNPs) in GLUT3… read more here.
Keywords: glucose transporter; patients non; dfs; non small ... See more keywords
Impact of tumor deposits on the prognosis and chemotherapy efficacy in stage III colorectal cancer patients with different lymph node status: A retrospective cohort study in China.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of surgery"
DOI: 10.1016/j.ijsu.2018.06.029
Abstract: BACKGROUND The goal was to determine whether tumor deposits (TDs) had effects on the overall survival (OS), cancer-specific survival (CSS), disease-free survival (DFS) and responses to chemotherapy in advanced colorectal cancer (CRC) patients with different… read more here.
Keywords: chemotherapy; stage iii; dfs; cancer ... See more keywords
Experimental study and preliminary economic evaluation of enzymatic biodiesel production by an integrated process using co-products from palm (Elaeais guineensis Jaquim) industry
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DOI: 10.1016/j.indcrop.2020.112904
Abstract: Abstract In the present work, biodiesel esters were produced by enzymatic reaction of Palm Fatty Acid Distillate (PFAD) with ethanol using a dry fermented solid (DFS) with lipase activity obtained by Solid-State Fermentation (SSF) in… read more here.
Keywords: biocatalyst; dfs; integrated process; process ... See more keywords
A lignan induces lysosomal dependent degradation of FoxM1 protein to suppress β-catenin nuclear translocation
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DOI: 10.1038/srep45951
Abstract: Colon cancer is one of the most common cancers. In this study, we isolated a lignan [(−)-(2R,3R)-1,4-O-diferuloylsecoisolariciresinol, DFS] from Alnus japonica (Betulaceae) and investigated its biological activity and mechanism of action on colon cancer. DFS… read more here.
Keywords: lysosomal dependent; foxm1 protein; degradation; dfs ... See more keywords
A Lignan from Alnus japonica Activates Myogenesis and Alleviates Dexamethasone-induced Myotube Atrophy
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DOI: 10.1055/a-1891-3366
Abstract: Abstract To find inhibitors against skeletal muscle loss, we isolated a lignan compound ((−)-(2 R ,3 R -1,4-O-diferuloylsecoisolarciresinol, DFS) from the stem of Alnus japonica . C2C12 myoblasts were treated with DFS during differentiation. To… read more here.
Keywords: dfs; alnus japonica; japonica; dexamethasone induced ... See more keywords
Joint estimation of (co) variance components and breeding values for mean and dispersion of days from calving to first service in Holstein cow
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DOI: 10.1071/an15643
Abstract: The present study explored the possibility of selection for uniformity of days from calving to first service (DFS) in dairy cattle. A double hierarchical generalised linear model with an iterative reweighted least-squares algorithm was used… read more here.
Keywords: mean dispersion; first service; dispersion; dfs ... See more keywords
Management and outcomes after neoadjuvant treatment for locally advanced breast cancer in older versus younger women
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DOI: 10.1080/0284186x.2022.2137844
Abstract: Abstract Aim This study examined treatment and survival among women with locally advanced breast cancer (LABC) through comparative analyses of women ≥70 years and those read more here.
Keywords: locally advanced; year; dfs; surgery ... See more keywords