Evaluation of soluble carbonic anhydrase IX as predictive marker for efficacy of bevacizumab: A biomarker analysis from the geparquinto phase III neoadjuvant breast cancer trial
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32163
Abstract: We analyzed the predictive potential of pretreatment soluble carbonic anhydrase IX levels (sCAIX) for the efficacy of bevacizumab in the phase III neoadjuvant GeparQuinto trial. sCAIX was determined by enzyme‐linked immunosorbent assay (ELISA). Correlations between… read more here.
Keywords: soluble carbonic; carbonic anhydrase; bevacizumab; efficacy bevacizumab ... See more keywords
The prognostic and clinicopathological value of tumor-associated macrophages in patients with colorectal cancer: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-020-03686-9
Abstract: There is a growing literature on the significance of tumor-associated macrophages (TAMs) in colorectal cancer (CRC). However, the role of TAMs in predicting the prognosis of CRC remains controversial. The current study aims to determine… read more here.
Keywords: tumor associated; density; dfs; cancer ... See more keywords
Inhibition of autophagy sensitizes lignan-induced endoplasmic reticulum stress-mediated cell death.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.03.081
Abstract: Relationship between autophagy and endoplasmic reticulum (ER) stress and their application to treat cancer have been actively studied these days. Recently, a lignan [(-)-(2R, 3R)-1,4-O-diferuloylsecoisolariciresinol, DFS] from Alnus japonica has been found to reduce the… read more here.
Keywords: cancer; dfs; endoplasmic reticulum; reticulum stress ... See more keywords
Utility of the CPS + EG scoring system in triple-negative breast cancer treated with neoadjuvant chemotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of cancer"
DOI: 10.1016/j.ejca.2021.05.027
Abstract: BACKGROUND Pathological complete response (pCR) after neoadjuvant chemotherapy (NACT) is associated with superior survival. This association is strongest in triple-negative breast cancer (TNBC). The CPS + EG system, based on pre-treatment clinical (CS) and post-treatment pathological stage… read more here.
Keywords: negative breast; year; cps; breast cancer ... See more keywords
Glucose transporter 3 gene variant is associated with survival outcome of patients with non-small cell lung cancer after surgical resection.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.04.013
Abstract: This study was conducted to explore whether polymorphisms of glucose transporter 3 (GLUT3) gene affect the prognosis of patients with non-small cell lung cancer (NSCLC) after surgical resection. Four single nucleotide polymorphisms (SNPs) in GLUT3… read more here.
Keywords: glucose transporter; patients non; dfs; non small ... See more keywords
Impact of tumor deposits on the prognosis and chemotherapy efficacy in stage III colorectal cancer patients with different lymph node status: A retrospective cohort study in China.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of surgery"
DOI: 10.1016/j.ijsu.2018.06.029
Abstract: BACKGROUND The goal was to determine whether tumor deposits (TDs) had effects on the overall survival (OS), cancer-specific survival (CSS), disease-free survival (DFS) and responses to chemotherapy in advanced colorectal cancer (CRC) patients with different… read more here.
Keywords: chemotherapy; stage iii; dfs; cancer ... See more keywords
Experimental study and preliminary economic evaluation of enzymatic biodiesel production by an integrated process using co-products from palm (Elaeais guineensis Jaquim) industry
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DOI: 10.1016/j.indcrop.2020.112904
Abstract: Abstract In the present work, biodiesel esters were produced by enzymatic reaction of Palm Fatty Acid Distillate (PFAD) with ethanol using a dry fermented solid (DFS) with lipase activity obtained by Solid-State Fermentation (SSF) in… read more here.
Keywords: biocatalyst; dfs; integrated process; process ... See more keywords
Assessing the Influence of Observations in Ensemble‐Based Data Assimilation Systems
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Advances in Modeling Earth Systems"
DOI: 10.1029/2024ms004809
Abstract: The skill of numerical weather forecasts strongly depends on the quality of the initial conditions (analyses), which are created by assimilating observations into previous short‐range model forecasts. Therefore, it is important to carefully assess the… read more here.
Keywords: influence; data assimilation; ensemble based; assimilation systems ... See more keywords
Prognostic and predictive capacity of tumor infiltrating lymphocytes in the MA.20 regional node radiotherapy trial
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DOI: 10.1038/s41523-025-00821-z
Abstract: Prognostic and predictive value of immune infiltrates in the context of regional nodal radiation (RNI) for breast cancer has not been assessed. Stromal tumor infiltrating lymphocytes (sTILs) were assessed on scanned images of hematoxylin and… read more here.
Keywords: cd8 stils; prognostic predictive; tumor infiltrating; dfs ... See more keywords
Efficacy of neoadjuvant immunochemotherapy and survival surrogate analysis of neoadjuvant treatment in IB–IIIB lung squamous cell carcinoma
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DOI: 10.1038/s41598-024-54371-8
Abstract: Until now, there are still few comparisons between neoadjuvant immunochemotherapy and chemotherapy as first-line treatment for patients with stage IB-IIIB lung squamous cell carcinoma (LUSC). In addition, the ability of pathologic response to predict long-term… read more here.
Keywords: survival; response; group; chemotherapy ... See more keywords
A lignan induces lysosomal dependent degradation of FoxM1 protein to suppress β-catenin nuclear translocation
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep45951
Abstract: Colon cancer is one of the most common cancers. In this study, we isolated a lignan [(−)-(2R,3R)-1,4-O-diferuloylsecoisolariciresinol, DFS] from Alnus japonica (Betulaceae) and investigated its biological activity and mechanism of action on colon cancer. DFS… read more here.
Keywords: lysosomal dependent; foxm1 protein; degradation; dfs ... See more keywords