Biochemical effects of deferasirox and deferasirox-loaded nanomicellesin iron-intoxicated rats.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119146
Abstract: Deferasirox (DFX) was formulated into oil-in-water microemulsions in the presence of pluronicto improve its oral bioavailability. The size of the DFX-loadedmicroemulsions system measured by dynamic light scattering (DLS) was about 9 nm. The anti-proliferative and anti-lipid… read more here.
Keywords: loaded microemulsions; iron intoxicated; dfx loaded; free dfx ... See more keywords
Preparation of pH-Responsive Vesicular Deferasirox: Evidence from In Silico, In Vitro, and In Vivo Evaluations
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DOI: 10.1021/acsomega.1c03816
Abstract: pH-sensitive nanocarriers can effectively deliver anticancer drugs to tumors and reduce the adverse effects of conventional chemotherapy. In this light, we prepared a novel pH-responsive deferasirox (DFX)-loaded vesicle and comprehensively performed in silico, in vitro,… read more here.
Keywords: niosomal dfx; vitro vivo; silico vitro; deferasirox ... See more keywords
Add-on Milnacipran Boosts Methylphenidate Response in an Adolescent With Attention-Deficit/Hyperactivity Disorder With Comorbid Anxiety and Enuresis.
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Therapeutics"
DOI: 10.1097/mjt.0000000000000884
Abstract: generally well controlled after switching from DFXDT to DFX-G. This finding indicates that the DFX formulation can be switched without a loss of efficacy if appropriate doses are used. The requirement for drug administration before… read more here.
Keywords: boosts methylphenidate; response adolescent; milnacipran boosts; methylphenidate response ... See more keywords
Treatment With Topical Deferoxamine Improves Cutaneous Vascularity and Tissue Pliability in an Irradiated Animal Model of Tissue Expander–Based Breast Reconstruction
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Plastic Surgery"
DOI: 10.1097/sap.0000000000001655
Abstract: Purpose Postmastectomy radiation therapy is an important component of the multimodality approach to later-stage breast cancers. Unfortunately, despite its proven survival benefits, postmastectomy radiation therapy is deleterious to the skin and soft tissue, causing increased… read more here.
Keywords: treatment; dfx; tissue; group ... See more keywords
Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety Comparison of Deferasirox Formulations for Treatment Tailoring
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DOI: 10.1182/blood-2019-122030
Abstract: Introduction: The majority of published data about Deferasirox (DFX) are obtained on the dispersible formulation (DFX DT). A film-coated formulation (DFX FCT) with higher bioavailability is now approved and used in most countries, in tablets… read more here.
Keywords: dfx fct; treatment; safety; formulation ... See more keywords
Deferoxamine Supplementation Abolished Iron-Related Toxicity of Ilex paraguariensis Extract: Behavioral and Biochemical Evaluation in Adult Zebrafish (Danio rerio)
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11081507
Abstract: Ilex paraguariensis (Herb mate) is a native plant from South America, widely consumed through the infusion of dried leaves. The presence of antioxidant properties in herb mate may be relevant and contribute to evaluating the… read more here.
Keywords: supplementation; ilex paraguariensis; paraguariensis; dfx ... See more keywords
Delafloxacin-Capped Gold Nanoparticles (DFX-AuNPs): An Effective Antibacterial Nano-Formulation of Fluoroquinolone Antibiotic
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DOI: 10.3390/ma15165709
Abstract: New antibiotics are seen as ‘drugs of last resort’ against virulent bacteria. However, development of resistance towards new antibiotics with time is a universal fact. Delafloxacin (DFX) is a new fluoroquinolone antibiotic that differs from… read more here.
Keywords: nano; fluoroquinolone antibiotic; dfx aunps; dfx ... See more keywords