Evaluation of non-synonym mutation in DGAT1 K232A as a marker for milk production traits in Ongole cattle and Murrah buffalo from Southern India
Sign Up to like & getrecommendations! Published in 2021 at "Tropical Animal Health and Production"
DOI: 10.1007/s11250-021-02560-2
Abstract: Various candidate genes have been reported to affect milk yield and composition in dairy cattle. A non-synonymous mutation in the DGAT1 gene, i.e., K232A was reported to have a strong association with milk yield and… read more here.
Keywords: milk; k232a; production; ongole cattle ... See more keywords
DGAT1 protects against lipid induced-hepatic lipotoxicity in grass carp (Ctenopharyngodon idellus)
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2020.736328
Abstract: Abstract Farmed fish often suffers from fatty liver, which is characterized by the aberrant lipid accumulation. Lipid droplet is an intracellular organelle to store neutral lipid, and the formation of excessive lipid droplets in hepatocytes… read more here.
Keywords: lipid droplet; grass carp; dgat1;
Different DGAT1s vary widely in function and a targeted amino acid substitution enhances oil accumulation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of experimental botany"
DOI: 10.1093/jxb/erac084
Abstract: Triacylglycerols (TAGs) are the major component of plant storage lipids such as oils. Acyl-CoA:diacylglycerol acyltransferase (DGAT) catalyzes the final step of the Kennedy pathway, and is mainly responsible for plant oil accumulation. We previously found… read more here.
Keywords: dgat1s; dgat1; oil accumulation; amino acid ... See more keywords
Mutation c.-379 C>T in DGAT1 affects intramyocellular lipid content by altering MYOD1 binding affinity.
Sign Up to like & getrecommendations! Published in 2023 at "Animal genetics"
DOI: 10.1111/age.13313
Abstract: Intramuscular fat (IMF) is one of the most important indexes of pork taste quality. Diacylglycerol acyltransferase 1 (DGAT1), belonging to the acyl-coenzyme A: DGAT enzymes family, is a rate-limiting enzyme responsible for the final step… read more here.
Keywords: imf content; dgat1; muscle; 379 allele ... See more keywords
Analysis of Differentially Expressed Genes in Gastrocnemius Muscle between DGAT1 Transgenic Mice and Wild-Type Mice
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/5404682
Abstract: Adipose tissue was the major energy deposition site of the mammals and provided the energy for the body and released the external pressure to the internal organs. In animal production, fat deposition in muscle can… read more here.
Keywords: gastrocnemius muscle; mice; dgat1 transgenic; muscle dgat1 ... See more keywords
Effects of diacylglycerol O-acyltransferase 1 (DGAT1) on endoplasmic reticulum stress and inflammatory responses in adipose tissue of ketotic dairy cows.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of dairy science"
DOI: 10.3168/jds.2022-21989
Abstract: Adipose tissue of ketotic dairy cows exhibits greater lipolytic rate and signs of inflammation, which further aggravate the metabolic disorder. In nonruminants, the endoplasmic reticulum (ER) is a key organelle coordinating metabolic adaptations and cellular… read more here.
Keywords: dgat1; inflammatory responses; stress inflammatory; tissue ketotic ... See more keywords
An alternative angiosperm DGAT1 topology and potential motifs in the N-terminus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.951389
Abstract: The highly variable cytoplasmic N-terminus of the plant diacylglycerol acyltransferase 1 (DGAT1) has been shown to have roles in oligomerization as well as allostery; however, the biological significance of the variation within this region is… read more here.
Keywords: topology; topology potential; dgat1; alternative angiosperm ... See more keywords