DGMM: A Deep Learning-Genetic Algorithm Framework for Efficient Lead Optimization in Drug Discovery
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DOI: 10.1021/acs.jcim.5c01017
Abstract: Lead optimization in drug discovery faces the dual challenge of maintaining structural diversity while preserving core molecular features and optimizing the balance between biological activity and drug-like properties. To address these challenges, we introduce the… read more here.
Keywords: drug; optimization drug; dgmm; lead optimization ... See more keywords