Improving docosahexaenoic acid production by Schizochytrium sp. using a newly designed high‐oxygen‐supply bioreactor
Sign Up to like & getrecommendations! Published in 2017 at "Aiche Journal"
DOI: 10.1002/aic.15783
Abstract: A sufficiently high oxygen supply is crucial for high-cell-density cultivation of aerobic microorganisms, including Schizochytrium sp. We, therefore, designed a novel bioreactor enabling high-level oxygen supply, and its relevant process parameters and fermentation-stage characteristics were… read more here.
Keywords: bioreactor; dha; oxygen supply; schizochytrium ... See more keywords
A pilot study on the effect of early provision of dietary docosahexaenoic acid on testis development, functions, and sperm quality in rats exposed to prenatal ethanol.
Sign Up to like & getrecommendations! Published in 2019 at "Birth defects research"
DOI: 10.1002/bdr2.1614
Abstract: BACKGROUND Prenatal ethanol (EtOH) exposure is associated with adverse effect on the male reproductive function. Dietary docosahexaenoic acid (DHA) is known to improve testis function and sperm parameters, thereby male fertility. This study piloted whether… read more here.
Keywords: testis; prenatal ethanol; dha; etoh ... See more keywords
Lipids from the Marine World: Perspectives of an Organic Chemist†
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Lipid Science and Technology"
DOI: 10.1002/ejlt.201700166
Abstract: This report describes synthesis of novel structured triacylglycerols (TAGs) and diacylglyceryl ethers (DAGEs) of the 1-O-alkyl-sn-glycerol type constituting EPA and DHA as the sole fatty acids. One of two TAGs was comprised of a pure… read more here.
Keywords: methodology; epa dha; position; pure dha ... See more keywords
Improvement of docosahexaenoic acid fermentation from Schizochytrium sp. AB‐610 by staged pH control based on cell morphological changes
Sign Up to like & getrecommendations! Published in 2017 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201600249
Abstract: Schizochytrium sp. AB‐610 accumulates relatively higher amount of DHA‐rich lipid in the cells, and it was found that DHA yield was closely related to the cell morphology and pH value during fermentation period. DHA production… read more here.
Keywords: fermentation; schizochytrium 610; dha; schizochytrium ... See more keywords
Docosahexaenoic acid increased MeCP2 mediated mitochondrial respiratory complexes II and III enzyme activities in cortical astrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23002
Abstract: Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the methyl‐CpG‐binding protein 2 (MeCP2) in the neurons and glial cells of the central nervous system. Currently, therapeutics for RTT is aimed at restoring… read more here.
Keywords: iii enzyme; docosahexaenoic acid; expression; dha ... See more keywords
Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26641
Abstract: Docosahexaenoic acid (DHA) and sodium butyrate (NaBt) exhibit a number of interactive effects on colon cancer cell growth, differentiation, or apoptosis; however, the molecular mechanisms responsible for these interactions and their impact on cellular lipidome… read more here.
Keywords: docosahexaenoic acid; colon; dha; colon cancer ... See more keywords
Dihydroartemisinin increases gemcitabine therapeutic efficacy in ovarian cancer by inducing reactive oxygen species
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DOI: 10.1002/jcb.27421
Abstract: Ovarian cancer is the major cause of death in women gynecological malignancy and gemcitabine (GEM) is commonly used in related chemotherapy. However, more than 90% GEM is catalyzed into an inactive metabolite 2′‐deoxy‐2′,2′‐difluorouridine by stromal… read more here.
Keywords: reactive oxygen; gem; oxygen species; dha ... See more keywords
Docosahexaenoic acid-acylated astaxanthin monoester ameliorates chronic high-fat diet-induced autophagy dysfunction via ULK1 pathway in the hypothalamus of mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12429
Abstract: BACKGROUND Dietary astaxanthin (AST) exhibits the ability to resist lipid accumulation and stimulate hepatic autophagy. Natural AST predominantly exists in more stable esterified forms. More importantly, in our previous study, docosahexaenoic acid-acylated AST monoester (AST-DHA)… read more here.
Keywords: docosahexaenoic acid; fat diet; acid acylated; dha ... See more keywords
Anti-inflammatory activity of β-caryophyllene combined with docosahexaenoic acid in a model of sepsis induced by Staphylococcus aureus in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.9861
Abstract: BACKGROUND Sepsis is a set of serious organic manifestations caused by an infection, whose progression culminates in exacerbated inflammation and oxidative stress, poor prognosis, and high hospital costs. Antioxidants used against sepsis have been evaluated,… read more here.
Keywords: anti inflammatory; sepsis; docosahexaenoic acid; inflammatory activity ... See more keywords
Higher Increase in Plasma DHA in Females Compared to Males Following EPA Supplementation May Be Influenced by a Polymorphism in ELOVL2: An Exploratory Study.
Sign Up to like & getrecommendations! Published in 2020 at "Lipids"
DOI: 10.1002/lipd.12291
Abstract: Young adult females have higher blood docosahexaenoic acid (DHA), 22:6n-3 levels than males, and this is believed to be due to higher DHA synthesis rates, although DHA may also accumulate due to a longer half-life… read more here.
Keywords: dha females; increase plasma; epa supplementation; dha ... See more keywords
α-linolenic acid interconversion is sufficient as a source of longer chain ω-3 polyunsaturated fatty acids in humans: An opinion.
Sign Up to like & getrecommendations! Published in 2022 at "Lipids"
DOI: 10.1002/lipd.12355
Abstract: α-linolenic acid (αLNA) conversion into the functionally important ω-3 polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), has been regarded as inadequate for meeting nutritional requirements for these PUFA. This view is… read more here.
Keywords: epa dha; linolenic acid; source; dha ... See more keywords