Improving docosahexaenoic acid production by Schizochytrium sp. using a newly designed high‐oxygen‐supply bioreactor
Sign Up to like & getrecommendations! Published in 2017 at "Aiche Journal"
DOI: 10.1002/aic.15783
Abstract: A sufficiently high oxygen supply is crucial for high-cell-density cultivation of aerobic microorganisms, including Schizochytrium sp. We, therefore, designed a novel bioreactor enabling high-level oxygen supply, and its relevant process parameters and fermentation-stage characteristics were… read more here.
Keywords: bioreactor; dha; oxygen supply; schizochytrium ... See more keywords
A pilot study on the effect of early provision of dietary docosahexaenoic acid on testis development, functions, and sperm quality in rats exposed to prenatal ethanol.
Sign Up to like & getrecommendations! Published in 2019 at "Birth defects research"
DOI: 10.1002/bdr2.1614
Abstract: BACKGROUND Prenatal ethanol (EtOH) exposure is associated with adverse effect on the male reproductive function. Dietary docosahexaenoic acid (DHA) is known to improve testis function and sperm parameters, thereby male fertility. This study piloted whether… read more here.
Keywords: testis; prenatal ethanol; dha; etoh ... See more keywords
UV Mutagenesis Enhances DHA Biosynthesis in Schizochytrium sp. via Metabolic Reprogramming
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DOI: 10.1002/biot.70107
Abstract: Schizochytrium sp., a marine alga prized for docosahexaenoic acid (DHA), was subjected to UV mutagenesis to boost industrial yields. The stable mutant UV1‐3 achieved 5.01 g/L DHA—40.34% higher than wild‐type S31. Transcriptomic and metabolomic analyses… read more here.
Keywords: dha production; mutagenesis; schizochytrium; dha biosynthesis ... See more keywords
Effects of Prenatal DHA Dose on Infant Visual Attention.
Sign Up to like & getrecommendations! Published in 2025 at "Developmental psychobiology"
DOI: 10.1002/dev.70072
Abstract: Prenatal supplementation with docosahexaenoic acid (DHA) has been reported to improve cognitive outcomes in infancy and early childhood in some studies. Existent studies have examined the effects of some dose of DHA against a true… read more here.
Keywords: prenatal dha; visual attention; attention; dha dose ... See more keywords
Lipids from the Marine World: Perspectives of an Organic Chemist†
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Lipid Science and Technology"
DOI: 10.1002/ejlt.201700166
Abstract: This report describes synthesis of novel structured triacylglycerols (TAGs) and diacylglyceryl ethers (DAGEs) of the 1-O-alkyl-sn-glycerol type constituting EPA and DHA as the sole fatty acids. One of two TAGs was comprised of a pure… read more here.
Keywords: methodology; epa dha; position; pure dha ... See more keywords
Improvement of docosahexaenoic acid fermentation from Schizochytrium sp. AB‐610 by staged pH control based on cell morphological changes
Sign Up to like & getrecommendations! Published in 2017 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201600249
Abstract: Schizochytrium sp. AB‐610 accumulates relatively higher amount of DHA‐rich lipid in the cells, and it was found that DHA yield was closely related to the cell morphology and pH value during fermentation period. DHA production… read more here.
Keywords: fermentation; schizochytrium 610; dha; schizochytrium ... See more keywords
28‐Day Repeated Dose Toxicity and Toxicokinetics Study on Dihydroartemisinin (DHA) in SD Rats
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4738
Abstract: Dihydroartemisinin (DHA) is an effective antimalarial drug with potential antitumor efficacy, yet toxicological information is limited. The present study was designed to evaluate the potential toxicity of oral DHA. DHA was administered orally by gavage… read more here.
Keywords: female rats; toxicity; dihydroartemisinin dha; dha ... See more keywords
Docosahexaenoic acid increased MeCP2 mediated mitochondrial respiratory complexes II and III enzyme activities in cortical astrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23002
Abstract: Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the methyl‐CpG‐binding protein 2 (MeCP2) in the neurons and glial cells of the central nervous system. Currently, therapeutics for RTT is aimed at restoring… read more here.
Keywords: iii enzyme; docosahexaenoic acid; expression; dha ... See more keywords
Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26641
Abstract: Docosahexaenoic acid (DHA) and sodium butyrate (NaBt) exhibit a number of interactive effects on colon cancer cell growth, differentiation, or apoptosis; however, the molecular mechanisms responsible for these interactions and their impact on cellular lipidome… read more here.
Keywords: docosahexaenoic acid; colon; dha; colon cancer ... See more keywords
Dihydroartemisinin increases gemcitabine therapeutic efficacy in ovarian cancer by inducing reactive oxygen species
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27421
Abstract: Ovarian cancer is the major cause of death in women gynecological malignancy and gemcitabine (GEM) is commonly used in related chemotherapy. However, more than 90% GEM is catalyzed into an inactive metabolite 2′‐deoxy‐2′,2′‐difluorouridine by stromal… read more here.
Keywords: reactive oxygen; gem; oxygen species; dha ... See more keywords
Pathways Contributing to Chemotherapy‐Induced Myotoxicity Are Attenuated by EPA + DHA in a Clinically Relevant Model of Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.70110
Abstract: Skeletal muscle loss is a well‐recognized consequence of cancer, and chemotherapy exacerbates myotoxicity through multiple mechanisms. Retaining muscle mass improves tumour response to therapies and tolerance to chemotherapy; hence, interventions to mitigate myotoxicity warrant investigations.… read more here.
Keywords: cancer; induced myotoxicity; chemotherapy; myotoxicity ... See more keywords