Engineered yeast for efficient de novo synthesis of 7‐dehydrocholesterol
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28055
Abstract: The synthesis of vitamin D3 precursor 7‐dehydrocholesterol (7‐DHC) by microbial fermentation has much attracted attention owing to its advantages of environmental protection. In this study, Saccharomyces cerevisiae was engineered for a de novo biosynthesis of… read more here.
Keywords: gene; dehydrocholesterol; dhc titer; synthesis ... See more keywords
Reengineering of 7-dehydrocholesterol biosynthesis in Saccharomyces cerevisiae using combined pathway and organelle strategies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.978074
Abstract: 7-Dehydrocholesterol (7-DHC) is a widely used sterol and a precursor of several costly steroidal drugs. In this study, 7-DHC biosynthesis pathway was constructed and modified in Saccharomyces cerevisiae. Firstly, the biosynthesis pathway was constructed by… read more here.
Keywords: biosynthesis; dehydrocholesterol; dhc; saccharomyces cerevisiae ... See more keywords