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Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.12.079
Abstract: Estrogen deficiency results in an imbalance between the levels of bone-resorping osteoclasts and bone-forming osteoblasts, eventually leading to overall bone loss. Dehydrodiconiferyl alcohol (DHCA), a lignan compound originally isolated from Cucurbita moschata, has been shown…
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Keywords:
dhca;
induced osteoblastogenesis;
bmp induced;
osteoblastogenesis ... See more keywords
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Published in 2020 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000619076.92191.53
Abstract: Introduction/Hypothesis: The pathologic tissue and urine metabolic fingerprints of cardiac surgery-induced acute kidney injury (AKI) have not been well defined. In this study, we utilized a porcine model of infant cardiopulmonary bypass (CPB) with deep…
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Keywords:
surgery induced;
tissue;
dhca;
cardiac surgery ... See more keywords
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Published in 2019 at "Artificial organs"
DOI: 10.1111/aor.13407
Abstract: Brain injury associated with deep hypothermic circulatory arrest (DHCA) has been recognized in patients with congenital heart diseases and those undergoing aortic arch surgeries. However, the preclinical investigation of long-term cerebral injury and recovery mechanisms…
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Keywords:
recovery;
long term;
dhca;
model ... See more keywords
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Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17165
Abstract: Deep hypothermic circulatory arrest (DHCA) can cause acute lung injury (ALI), and its pathogenesis mimics ischaemia/reperfusion (I/R) injury. Autophagy is also involved in lung I/R injury. The present study aimed to elucidate whether DHCA induces…
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Keywords:
dhca;
lung injury;
role;
injury ... See more keywords
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Published in 2023 at "Brain Sciences"
DOI: 10.3390/brainsci13030525
Abstract: Objectives: Postoperative neurological deficits remain a challenge in cardiac surgery employing deep hypothermic circulatory arrest (DHCA). This study aimed to investigate the effect of WIN55, 212-2, a cannabinoid agonist, on brain injury in a rat…
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Keywords:
circulatory arrest;
win55 212;
dhca;
deep hypothermic ... See more keywords