Articles with "dhhc3" as a keyword



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Structural Exploration on Palmitoyltransferase DHHC3 from Homo sapiens

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Published in 2022 at "Polymers"

DOI: 10.3390/polym14153013

Abstract: DHHC3 belongs to a family of DHHC palmitoyltransferase, which catalyzes the S-palmitoylation of target proteins by attaching a fatty acyl group to a cysteine. Recently, DHHC3 has been demonstrated to be a promising antitumor target… read more here.

Keywords: palmitoyltransferase dhhc3; structural exploration; dhhc3; exploration palmitoyltransferase ... See more keywords
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Recent progress of palmitoyl transferase DHHC3 as a novel antitumor target.

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Published in 2022 at "Future medicinal chemistry"

DOI: 10.4155/fmc-2021-0192

Abstract: DHHC3 is a DHHC-family palmitoyl acyltransferase that is responsible for many mammalian palmitoylation events. By regulating the posttranslational modification of its specific substrates, DHHC3 has shown a strong protumor effect in various cancers. In this… read more here.

Keywords: antitumor target; dhhc3; recent progress;