Teriflunomide Treatment of Multiple Sclerosis Selectively Modulates CD8 Memory T Cells
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DOI: 10.3389/fimmu.2021.730342
Abstract: Background and Objectives Inhibition of de novo pyrimidine synthesis in proliferating T and B lymphocytes by teriflunomide, a pharmacological inhibitor of dihydroorotate dehydrogenase (DHODH), has been shown to be an effective therapy to treat patients… read more here.
Keywords: cd8; treatment; dhodh inhibition; patients rrms ... See more keywords