Dihydroorotate Dehydrogenase Inhibitors Promote Cell Cycle Arrest and Disrupt Mitochondria Bioenergetics in Ramos Cells.
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DOI: 10.2174/1389201021666200611113734
Abstract: BACKGROUND The re-emerging of targeting dihydroorotate dehydrogenase (DHODH) in cancer treatment particularly acute myelogenous leukemia (AML) have corroborated the substantial role of DHODH in cancer and fascinated the attention of many pharmaceutical industries. OBJECTIVE The… read more here.
Keywords: cell cycle; dhodh inhibitors; dhodh; cell ... See more keywords