Acetylated Hyaluronic Acid-Poly(L-lactic acid) Conjugate Nanoparticles for Inhibition of Doxorubicinol Production from Doxorubicin
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular Research"
DOI: 10.1007/s13233-020-8003-6
Abstract: In this study, doxorubicin (DOX)-induced cardiotoxicity was overcome using cancer-recognizable DOX-loaded acetylated hyaluronic aicd-poly(L-lactic acid) (AcHA-PLLA) nanoparticles (DHPs). AcHA-PLLA was synthesized via ring opening polymerization of L-lactide with AcHA as a macroinitiator and characterized by… read more here.
Keywords: dhps; poly lactic; doxorubicinol; dox ... See more keywords
Polymorphisms in Plasmodium falciparum dihydropteroate synthetase and dihydrofolate reductase genes in Nigerian children with uncomplicated malaria using high-resolution melting technique
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80017-6
Abstract: In 2005, the Nigerian Federal Ministry of Health revised the treatment policy for uncomplicated malaria with the introduction of artemisinin-based combination therapies (ACTs). This policy change discouraged the use of Sulphadoxine-pyrimethamine (SP) as the second-line… read more here.
Keywords: dhps; high resolution; dihydropteroate synthetase; resolution melting ... See more keywords
Plasmodium falciparum dhps and dhfr markers of resistance to sulfadoxine–pyrimethamine five years (2016–2020) after the implementation of seasonal malaria chemoprevention in Cameroon
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DOI: 10.12688/wellcomeopenres.22347.1
Abstract: Background Antimalarial drug resistance is a major challenge in the fight against malaria. Cameroon implemented seasonal malaria chemoprevention (SMC) with sulfadoxine–pyrimethamine and amodiaquine (SPAQ) to over 1.5 million children aged 3–59 months from 2016, raising… read more here.
Keywords: falciparum; dhps; dhfr; cameroon ... See more keywords
Manipulation of DHPS activity affects dendritic morphology and expression of synaptic proteins in primary rat cortical neurons
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2024.1465011
Abstract: Deoxyhypusine synthase (DHPS) catalyzes the initial step of hypusine incorporation into the eukaryotic initiation factor 5A (eIF5A), leading to its activation. The activated eIF5A, in turn, plays a key role in regulating the protein translation… read more here.
Keywords: activity affects; manipulation dhps; dhps; affects dendritic ... See more keywords