Evolution of DNAase I Hypersensitive Sites in MHC Regulatory Regions of Primates
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DOI: 10.1534/genetics.118.301028
Abstract: Jin et al. report thousands of DNAseI hypersensitive sites in the MHC region that have been gained or lost in primate genomes since their evolutionary divergence, identifying 24 that evolved rapidly in the human lineage...… read more here.
Keywords: dnaase hypersensitive; sites mhc; hypersensitive sites; evolution dnaase ... See more keywords
Unveiling the gene regulatory landscape in diseases through the identification of DNase I-hypersensitive sites
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DOI: 10.3892/br.2019.1233
Abstract: DNase I-hypersensitive sites (DHSs) serve key roles in the regulation of gene transcription as markers of cis-regulatory elements (CREs). Recent advances in next-generation sequencing have enabled the genome-wide location and annotation of DHSs in a… read more here.
Keywords: hypersensitive sites; dnase hypersensitive; dhss; identification ... See more keywords