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Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32310
Abstract: Earlier cohort studies using conventional regression models have consistently shown an increased cancer risk among individuals with type 2 diabetes. However, reverse causality and residual confounding due to common risk factors could exist, and it…
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Keywords:
risk;
mendelian randomization;
study;
cancer risk ... See more keywords
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Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-65768-0_16
Abstract: Diabetes mellitus, commonly known as diabetes, and cancer are two of the most common diseases plaguing the world today. According to the Centers for Disease Control and Prevention (CDC), there are currently more than 20…
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Keywords:
cancer epidemiological;
metabolic associations;
biology;
epidemiological metabolic ... See more keywords
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Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.02.017
Abstract: The incidence of both cancer and diabetes is dramatically increasing in worldwide population, costing many millions from governments into expenditures related to medical health systems. Diabetes has been clinically linked to an increased risk for…
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Keywords:
ca2 camp;
cancer;
diabetes cancer;
cancer debating ... See more keywords
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Published in 2020 at "Drug discovery today"
DOI: 10.1016/j.drudis.2020.07.003
Abstract: The irreversible glycation and oxidation of proteins and lipids produces advanced glycation end products (AGEs). These modified AGEs are triggered to bind the receptor for AGE (RAGE), thereby activating its downstream signaling pathways, such as…
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Keywords:
products diabetes;
end products;
glycation end;
advanced glycation ... See more keywords
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Published in 2019 at "Diabetic Medicine"
DOI: 10.1111/dme.13919
Abstract: Although micro‐ and macrovascular complications of diabetes are the most important cause of mortality and morbidity in people with diabetes, it is increasingly recognized that diabetes increases the risk of developing cancer. Diabetes and cancer…
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Keywords:
management people;
people diabetes;
challenges management;
cancer ... See more keywords
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Published in 2023 at "Diabetic Medicine"
DOI: 10.1111/dme.15043
Abstract: Diabetes is associated with a higher risk of colorectal cancer (CRC) and inferior survival after CRC. Screening may enable the early detection of CRC. We aimed to assess the impact of diabetes on cancer detection…
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Keywords:
detection;
colorectal cancer;
diabetes cancer;
cancer detection ... See more keywords
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Published in 2019 at "Critical reviews in oncogenesis"
DOI: 10.1615/critrevoncog.2019032959
Abstract: Obesity leads to many diseases including hypercholesterolemia, type-2 diabetes, hypertension, cardiovascular disease, and cancer. It is the fastest-growing lethal disease in the Western and developing countries. The link between obesity and cancer is relatively underappreciated…
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Keywords:
obesity;
type diabetes;
obesity type;
diabetes cancer ... See more keywords
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Published in 2017 at "Current pharmaceutical design"
DOI: 10.2174/1381612823666170714141450
Abstract: GSK3 has gained a considerable attention of researchers in the late 1970s as an inevitable drug target to treat diabetes. Furthermore, it was found to have a key role in the development of diseases like…
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Keywords:
cancer neurodegeneration;
gsk3;
gsk3 inhibitors;
diabetes cancer ... See more keywords
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Published in 2022 at "JMIR mHealth and uHealth"
DOI: 10.2196/32344
Abstract: Background Major chronic diseases such as cardiovascular disease (CVD), diabetes, and cancer impose a significant burden on people and health care systems around the globe. Recently, deep learning (DL) has shown great potential for the…
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Keywords:
review;
diabetes cancer;
cancer;
learning ... See more keywords
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Published in 2018 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00388
Abstract: Pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, works as cofactor in numerous enzymatic reactions and it behaves as antioxidant molecule. PLP deficiency has been associated to many human pathologies including cancer and diabetes…
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Keywords:
plp;
vitamin diabetes;
cancer;
vitamin ... See more keywords
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Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.615375
Abstract: Obesity and type 2 diabetes have both been associated with increased cancer risk and are becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and dyslipidemia are associated with both obesity and type 2 diabetes…
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Keywords:
obesity type;
type diabetes;
cancer;
obesity ... See more keywords