Genetic Control of Splicing at SIRPG Modulates Risk of Type 1 Diabetes.
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes"
DOI: 10.2337/db21-0194
Abstract: Signal regulatory protein SIRPĪ³ (CD172G) is expressed on the surface of lymphocytes where it acts by engaging its ligand, CD47. SIRPG, which encodes SIRPĪ³, contains a non-synonymous coding variant, rs6043409, which is significantly associated with… read more here.
Keywords: risk type; transcript isoforms; type diabetes; sirpg ... See more keywords
A Diabetes Genetic Risk Score Is Associated With All-Cause Dementia and Clinically Diagnosed Vascular Dementia in the Million Veteran Program.
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes care"
DOI: 10.2337/dc22-0105
Abstract: OBJECTIVE Diabetes and dementia are diseases of high health care burden worldwide, and studies have shown that diabetes is associated with an increased relative risk of dementia. We set out to examine whether type 2… read more here.
Keywords: diabetes genetic; risk; dementia; clinically diagnosed ... See more keywords