HDAC4 mutations cause diabetes and induce β‐cell FoxO1 nuclear exclusion
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DOI: 10.1002/mgg3.602
Abstract: Studying patients with rare Mendelian diabetes has uncovered molecular mechanisms regulating β‐cell pathophysiology. Previous studies have shown that Class IIa histone deacetylases (HDAC4, 5, 7, and 9) modulate mammalian pancreatic endocrine cell function and glucose… read more here.
Keywords: diabetes induce; cause diabetes; induce cell; hdac4 mutations ... See more keywords