Heterogeneous Development of β-Cell Populations in Diabetes-Resistant and -Susceptible Mice
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.2337/db21-1030
Abstract: Progressive dysfunction and failure of insulin-releasing β-cells are a hallmark of type 2 diabetes (T2D). To study mechanisms of β-cell loss in T2D, we performed islet single-cell RNA sequencing of two obese mouse strains differing… read more here.
Keywords: cell; diabetes prone; development; prone mice ... See more keywords
Lactobacillus johnsonii N6.2 diminishes caspase-1 maturation in the gastrointestinal system of diabetes prone rats.
Sign Up to like & getrecommendations! Published in 2018 at "Beneficial microbes"
DOI: 10.3920/bm2017.0120
Abstract: The cells of the gastrointestinal (GI) epithelium are the first to contact the microbiota and food components. As a direct consequence of this, these cells are the first line of defence and key players in… read more here.
Keywords: caspase; prone rats; diabetes prone; kynurenine pathway ... See more keywords