Study design choices for evaluating the comparative safety of diabetes medications: An evaluation of pioglitazone use and risk of bladder cancer in older US adults with type‐2 diabetes
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DOI: 10.1111/dom.13774
Abstract: The aim of the study was to empirically demonstrate the effect of varying study designs when evaluating the safety of pioglitazone in treating bladder cancer. read more here.
Keywords: pioglitazone; bladder cancer; diabetes study; safety ... See more keywords
Incidence and predictors of idiopathic pulmonary fibrosis complicating Type 2 diabetes: the Fremantle Diabetes Study Phase I
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DOI: 10.1111/imj.15191
Abstract: During 106 865 person‐years of follow up, 17 (1.3%) Fremantle Diabetes Study Phase I participants with Type 2 diabetes and 57 (1.1%) matched individuals without diabetes developed idiopathic pulmonary fibrosis (IPF), an incidence rate ratio (95%… read more here.
Keywords: study phase; idiopathic pulmonary; fremantle diabetes; diabetes study ... See more keywords
The relationship between pancreatic cancer and type 2 diabetes: the Fremantle Diabetes Study Phase I
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DOI: 10.1111/imj.15846
Abstract: Pancreatic cancer incidence was double (incidence rate ratio 2.06) in community‐based adults with (n = 1291) versus without (n = 5158) type 2 diabetes followed for up to 25 years in the Fremantle Diabetes Study Phase 1. Sustained… read more here.
Keywords: fremantle diabetes; pancreatic cancer; diabetes study; study phase ... See more keywords
A study on pharmacokinetics, pharmacodynamics and safety of lixisenatide in children and adolescents with type 2 diabetes
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DOI: 10.1111/pedi.13343
Abstract: The aim of this study was to investigate the pharmacokinetic, pharmacodynamic and safety profile of the glucagon‐like peptide‐1 receptor agonist, lixisenatide, for the treatment of type 2 diabetes (T2D) in pediatric individuals. read more here.
Keywords: safety; pharmacokinetics pharmacodynamics; diabetes study; pharmacodynamics safety ... See more keywords
Retinopathy predicts stroke but not myocardial infarction in type 2 diabetes: the Fremantle Diabetes Study Phase II
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DOI: 10.1186/s12933-020-01018-3
Abstract: Background Microangiopathy in type 2 diabetes (T2D) is associated with cardiovascular disease (CVD), but most relevant studies were performed > 10 years ago. CVD risk factor management has since improved. The aim of this study was to determine… read more here.
Keywords: risk; fremantle diabetes; myocardial infarction; diabetes study ... See more keywords
Effects of Lysulin™ supplementation on pre-diabetes: study protocol for a randomized controlled trial
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DOI: 10.1186/s13063-019-3269-8
Abstract: BackgroundDiabetes mellitus is rapidly becoming one of the leading causes of morbidity and mortality worldwide. Preventive measures have become important, especially in the South Asian region and other parts of the world where diabetes is… read more here.
Keywords: pre diabetes; trial; randomized controlled; effects lysulin ... See more keywords
Circulating Palmitoyl Sphingomyelin Is Associated With Cardiovascular Disease in Individuals With Type 2 Diabetes: Findings From the China Da Qing Diabetes Study
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DOI: 10.2337/dc21-1520
Abstract: OBJECTIVE To investigate the association of potential cardiovascular disease (CVD) biomarkers in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: We enrolled 120 participants (aged 61.5–69.5 years) with type 2 diabetes and 60 (aged… read more here.
Keywords: cvd risk; qing diabetes; cardiovascular disease; diabetes study ... See more keywords