Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 11
Sign Up to like & getrecommendations! Published in 2018 at "Mammalian Genome"
DOI: 10.1007/s00335-018-9742-y
Abstract: Streptozotocin (STZ) has been widely used to induce diabetes in rodents. Strain-dependent variation in susceptibility to STZ has been reported; however, the gene(s) responsible for STZ susceptibility has not been identified. Here, we utilized the… read more here.
Keywords: susceptibility; stz; diabetes susceptibility; induced diabetes ... See more keywords
Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.
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DOI: 10.1016/j.celrep.2017.02.019
Abstract: Plasma metabolite concentrations reflect the activity of tissue metabolic pathways and their quantitative determination may be informative about pathogenic conditions. We searched for plasma lipid species whose concentrations correlate with various parameters of glucose homeostasis and… read more here.
Keywords: plasma; susceptibility; plasma dihydroceramides; diabetes susceptibility ... See more keywords
Nucleotide substitutions in CD101, the human homolog of a diabetes susceptibility gene in non‐obese diabetic mouse, in patients with type 1 diabetes
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DOI: 10.1111/jdi.12586
Abstract: Although genome‐wide association studies have identified more than 50 susceptibility genes for type 1 diabetes, low‐frequency risk variants could remain unrecognized. The present study aimed to identify novel type 1 diabetes susceptibility genes by newly… read more here.
Keywords: human homolog; diabetes susceptibility; cd101 human; substitutions cd101 ... See more keywords
Immunological Impacts of Diabetes on the Susceptibility of Mycobacterium tuberculosis
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DOI: 10.1155/2019/6196532
Abstract: The interaction between diabetes and major world infections like TB is a major public health concern because of rapidly rising levels of diabetes. The dual burden of tuberculosis (TB) and diabetes mellitus (DM) has become… read more here.
Keywords: susceptibility mycobacterium; diabetes susceptibility; immunological impacts; diabetes mellitus ... See more keywords