Swertisin, a novel SGLT2 inhibitor, with improved glucose homeostasis for effective diabetes therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.108995
Abstract: Failing pancreas and subsequent loss of pancreatic β cells worsen diabetic conditions which are further alleviated by the mounting up of glucose levels. Inhibition of sodium glucose cotransporter 2 (SGLT2) in the kidney responsible for… read more here.
Keywords: swertisin; glucose homeostasis; diabetes therapy; sglt2 ... See more keywords
The effects of diabetes therapy on bone: A clinical perspective.
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DOI: 10.1016/j.jdiacomp.2018.04.005
Abstract: The effects of diabetes and diabetes therapy on bone are less known among clinicians. Traditionally, the emphasis of diabetes therapy has been on reducing cardiovascular risk by facilitating reductions in weight, blood pressure, blood sugar,… read more here.
Keywords: effects diabetes; diabetes therapy; clinical perspective; therapy bone ... See more keywords
Microneedle-array patches loaded with dual mineralized protein/peptide particles for type 2 diabetes therapy
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DOI: 10.1038/s41467-017-01764-1
Abstract: The delivery of therapeutic peptides for diabetes therapy is compromised by short half-lives of drugs with the consequent need for multiple daily injections that reduce patient compliance and increase treatment cost. In this study, we… read more here.
Keywords: diabetes therapy; microneedle array; dual mineralized; array patches ... See more keywords
External Physical and Technical Influences on Medical Devices for Diabetes Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of diabetes science and technology"
DOI: 10.1177/19322968221080160
Abstract: Home and work situations can expose diabetes medical devices to a number of environmental factors that may influence their function and safety. In accordance with regulatory requirements, manufacturing companies take great care in the construction… read more here.
Keywords: technical influences; diabetes therapy; environmental factors; physical technical ... See more keywords
Diabetology 4.0: Scoping Review of Novel Insights and Possibilities Offered by Digitalization
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DOI: 10.2196/23475
Abstract: Background The increasing prevalence of diabetes mellitus and associated morbidity worldwide justifies the need to create new approaches and strategies for diabetes therapy. Therefore, the ongoing digitalization offers novel opportunities in this field. Objective The… read more here.
Keywords: diabetes therapy; scoping review; digitalization; novel insights ... See more keywords
Advances in type 2 diabetes therapy: a focus on cardiovascular and renal outcomes
Sign Up to like & getrecommendations! Published in 2020 at "Medical Journal of Australia"
DOI: 10.5694/mja2.50472
Abstract: Treatment options for type 2 diabetes have expanded. While metformin remains the first line treatment in most cases, choices for second line treatment now extend beyond sulfonylureas and include the sodium–glucose cotransporter 2 (SGLT2) inhibitors,… read more here.
Keywords: therapy focus; focus cardiovascular; diabetes therapy; cardiovascular renal ... See more keywords