Cardiac transcriptome profiling of diabetic Akita mice using microarray and next generation sequencing
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DOI: 10.1371/journal.pone.0182828
Abstract: Although diabetes mellitus (DM) causes cardiomyopathy and exacerbates heart failure, the underlying molecular mechanisms for diabetic cardiomyopathy/heart failure are poorly understood. Insulin2 mutant (Ins2+/-) Akita is a mouse model of T1DM, which manifests cardiac dysfunction.… read more here.
Keywords: heart; akita mice; diabetic akita; cardiac transcriptome ... See more keywords