HMOX1 upregulation promotes ferroptosis in diabetic atherosclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119935
Abstract: OBJECTIVE Atherosclerotic vascular disease remains the principal cause of death and disability among patients with type 2 diabetes. Unfortunately, the problem is not adequately resolved by therapeutic strategies with currently available drugs or approaches that… read more here.
Keywords: vascular disease; ferroptosis diabetic; atherosclerotic vascular; diabetic atherosclerosis ... See more keywords
Diabetic atherosclerosis: is there a role for the hypoxia-inducible factors?
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20200026
Abstract: Abstract Atherosclerosis is a major cause of mortality worldwide and is driven by multiple risk factors, including diabetes. Diabetes is associated with either an insulin deficiency in its juvenile form or with insulin resistance and… read more here.
Keywords: metabolic syndrome; hypoxia inducible; role; atherosclerosis ... See more keywords
Well-posedness of a mathematical model of diabetic atherosclerosis with advanced glycation end-products
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DOI: 10.1080/00036811.2022.2060210
Abstract: Atherosclerosis is a leading cause of death worldwide; it emerges as a result of multiple dynamical cell processes, including hemodynamics, endothelial damage, innate immunity and sterol biochemistry. Making matters worse, nearly 463 million people have… read more here.
Keywords: mathematical model; model diabetic; atherosclerosis; model ... See more keywords
Loss of OTUD6B Stimulates Angiogenesis and Promotes Diabetic Atherosclerosis
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DOI: 10.2147/dmso.s380986
Abstract: Purpose Angiogenesis is an essential promoter of atherosclerotic plaque rupture. However, the mechanism of its regulation is not understood. OTUD6B regulates cell proliferation, migration, and angiogenesis. We investigated the role of OTUD6B in angiogenesis in… read more here.
Keywords: proliferation migration; endothelial cells; atherosclerosis; diabetic atherosclerosis ... See more keywords
TUG1 promotes diabetic atherosclerosis by regulating proliferation of endothelial cells via Wnt pathway.
Sign Up to like & getrecommendations! Published in 2018 at "European Review for Medical and Pharmacological Sciences"
DOI: 10.26355/eurrev_201810_16162
Abstract: OBJECTIVE: To explore the specific role of TUG1 in regulating the occurrence and progression of diabetic atherosclerosis and its underlying mechanism. PATIENTS AND METHODS: TUG1 expressions in coronary artery disease (CAD) tissues, normal arterial tissues,… read more here.
Keywords: tug1; proliferation; endothelial cells; diabetic atherosclerosis ... See more keywords
Salvianolic acid A regulates pyroptosis of endothelial cells via directly targeting PKM2 and ameliorates diabetic atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1009229
Abstract: Rescuing endothelial cells from pyroptotic cell death emerges as a potential therapeutic strategy to combat diabetic atherosclerosis. Salvianolic acid A (SAA) is a major water-soluble phenolic acid in the Salvia miltiorrhiza Bunge, which has been… read more here.
Keywords: endothelial cells; pkm2; diabetic atherosclerosis; pyroptosis endothelial ... See more keywords