Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202590
Abstract: Diabetes manifests as chronic inflammation and leads to the development diabetic cardiomyopathy (DCM). Targeting key proteins in inflammatory signaling may provide new therapy for DCM. In this study, the authors explore the pharmacological effects and… read more here.
Keywords: inflammation; myd88; myd88 dependent; diabetic cardiomyopathy ... See more keywords
Cinnamic acid is beneficial to diabetic cardiomyopathy via its cardioprotective, anti‐inflammatory, anti‐dyslipidemia, and antidiabetic properties
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23215
Abstract: Diabetes‐related health issues are increasing day by day in public, and diabetic cardiomyopathy (DCM) is one serious issue among them. There is a lack of proper strategy to control and manage DCM. Here we are… read more here.
Keywords: diabetic rats; dcm; via cardioprotective; cinnamic acid ... See more keywords
Umbelliferone attenuates diabetic cardiomyopathy by suppression of JAK/STAT signaling pathway through amelioration of oxidative stress and inflammation in rats
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23296
Abstract: Umbelliferone (UMB), 7‐hydroxycoumarin, is a naturally occurring coumarin derivative that has a plethora of biological and therapeutic activities. The focus of this research was to elucidate the curative effects of two different doses of UMB… read more here.
Keywords: stat signaling; signaling pathway; oxidative stress; jak stat ... See more keywords
Matrine improves diabetic cardiomyopathy through TGF‐β‐induced protein kinase RNA‐like endoplasmic reticulum kinase signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28632
Abstract: Matrine might play a vital role in cardiovascular diseases progression and treatment. read more here.
Keywords: matrine improves; kinase; cardiomyopathy tgf; improves diabetic ... See more keywords
Combined treatment with systemic resveratrol and resveratrol preconditioned mesenchymal stem cells, maximizes antifibrotic action in diabetic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27947
Abstract: Wnt/β‐catenin signaling pathway plays a crucial role in diabetic cardiomyopathy (DCM), thus we aimed at investigating the effect of one therapeutic approach with resveratrol (RSV) given systemically and combined treatment of RSV with mesenchymal stem… read more here.
Keywords: resveratrol; rsv; mscs; diabetic cardiomyopathy ... See more keywords
Lin28a protects against diabetic cardiomyopathy through Mst1 inhibition
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29321
Abstract: Lin28a has been found to enhance glucose uptake and insulin sensitivity. Lin28a alleviates cardiac dysfunction under various pathological conditions. However, the effects and underlying mechanisms of Lin28a on diabetic cardiomyopathy (DCM) are not well‐understood. The… read more here.
Keywords: mst1; mst1 inhibition; high glucose; lin28a ... See more keywords
Ginkgo biloba extract protects against diabetic cardiomyopathy by restoring autophagy via adenosine monophosphate‐activated protein kinase/mammalian target of the rapamycin pathway modulation
Sign Up to like & getrecommendations! Published in 2023 at "Phytotherapy Research"
DOI: 10.1002/ptr.7746
Abstract: Studies demonstrated that Ginkgo biloba extract (GBE) played a cardioprotective role in diabetic conditions. Impaired autophagy is one of the mechanisms underlying diabetic cardiomyopathy (DCM). The effect of GBE on autophagy has been observed in… read more here.
Keywords: biloba extract; adenosine monophosphate; ginkgo biloba; monophosphate activated ... See more keywords
Targeting miRNA for Therapy of Juvenile and Adult Diabetic Cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-74470-4_4
Abstract: Prevalence of diabetes mellitus (DM), a multifactorial disease often diagnosed with high blood glucose levels, is rapidly increasing in the world. Association of DM with multi-organ dysfunction including cardiomyopathy makes it a leading cause of… read more here.
Keywords: adult diabetic; cardiomyopathy; juvenile adult; diabetic cardiomyopathy ... See more keywords
Pathological Effects of Exosomes in Mediating Diabetic Cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-10-4397-0_8
Abstract: Diabetic subjects are at risk of developing cardiovascular disease, which accounts for 60-80% of diabetes-related mortality. Atherosclerosis is still considered as a leading cause of heart failure in diabetic patients, but it could also be… read more here.
Keywords: exosomes mediating; mediating diabetic; pathological effects; diabetic cardiomyopathy ... See more keywords
Diabetic cardiomyopathy: a hyperglycaemia- and insulin-resistance-induced heart disease
Sign Up to like & getrecommendations! Published in 2017 at "Diabetologia"
DOI: 10.1007/s00125-017-4390-4
Abstract: Diabetic cardiomyopathy is characterised in its early stages by diastolic relaxation abnormalities and later by clinical heart failure in the absence of dyslipidaemia, hypertension and coronary artery disease. Insulin resistance, hyperinsulinaemia and hyperglycaemia are each… read more here.
Keywords: heart; diabetic cardiomyopathy; hyperglycaemia; insulin resistance ... See more keywords
Diabetic cardiomyopathy: How can cardiac magnetic resonance help?
Sign Up to like & getrecommendations! Published in 2020 at "Acta Diabetologica"
DOI: 10.1007/s00592-020-01528-2
Abstract: Diabetes cardiomyopathy is a specific form of cardiac disease characteristic for diabetic patients. Development of echocardiography enabled diagnosis of diabetic cardiomyopathy significantly before the occurrence of heart failure. Previously was believed that left ventricular (LV)… read more here.
Keywords: fibrosis; magnetic resonance; diabetic patients; cardiac magnetic ... See more keywords