Antioxidant and anti-glycated TAT-modified platinum nanoclusters as eye drops for non-invasive and painless relief of diabetic cataract in rats
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2020.125436
Abstract: Abstract Diabetic cataract (DC) is a kind of worrying ocular complications that eventually leads to blindness. However, there are a narrow range of pharmacological interventions to enable control the progression of DC, especially the eye… read more here.
Keywords: eye drops; non invasive; invasive painless; diabetic cataract ... See more keywords
Effects of microRNA-211 on proliferation and apoptosis of lens epithelial cells by targeting SIRT1 gene in diabetic cataract mice
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DOI: 10.1042/bsr20170695
Abstract: Our study aimed at exploring the effects of miR-211 on the proliferation and apoptosis of lens epithelial cells in diabetic cataract mice by targetting NAD+-dependent histone deacetylase sirtulin 1 (SIRT1). Healthy male mice were assigned… read more here.
Keywords: apoptosis; mir 211; proliferation; diabetic cataract ... See more keywords
Integrated Analysis of Long Non-Coding RNA -mRNA Profile and Validation in Diabetic Cataract
Sign Up to like & getrecommendations! Published in 2022 at "Current Eye Research"
DOI: 10.1080/02713683.2021.1984536
Abstract: ABSTRACT Purpose To illustrate the expression profile of lncRNAs and mRNAs in diabetic cataract (DC) and explore their potential role in the pathogenesis of DC. Methods LncRNA and mRNA microarray were conducted using the lens… read more here.
Keywords: expression; analysis; diabetic cataract; downregulated mrnas ... See more keywords
Identification of tRNA-derived fragments and their potential roles in diabetic cataract rats.
Sign Up to like & getrecommendations! Published in 2020 at "Epigenomics"
DOI: 10.2217/epi-2020-0193
Abstract: Aim: To illustrate the expression profile of transfer RNA-derived fragments and reveal their putative role in the pathogenesis of diabetic cataract (DC) rats. Materials & methods: Small RNA sequencing was conducted in the lens epithelium… read more here.
Keywords: identification trna; trna derived; cataract rats; diabetic cataract ... See more keywords