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Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2017.1388283
Abstract: Binding of acarbose, an anti-diabetic drug to lysozyme: a combined structural and thermodynamic study
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Keywords:
drug lysozyme;
diabetic drug;
acarbose anti;
anti diabetic ... See more keywords
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Published in 2020 at "Current Drug Therapy"
DOI: 10.2174/1574885515999200415114330
Abstract: Different experimental methods have been used to induce diabetes in animals. There are a number of anti-diabetic drug loaded nano-formulations with high therapeutic value that are used to target diabetes with high therapeutic efficacy. From…
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Keywords:
experimental methods;
therapeutic efficacy;
drug;
anti diabetic ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.929684
Abstract: Mitiglinide is a highly selective fast-acting anti-diabetic drug that inhibits pancreatic KATP channels to induce insulin secretion. However, how mitiglinide binds KATP channels remains unknown. Here, we show the cryo-EM structure of the SUR1 subunit…
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Keywords:
anti diabetic;
diabetic drug;
structural insights;
high selectivity ... See more keywords