Molecular Interaction of Anti‐Diabetic Drugs With Acetylcholinesterase and Sodium Glucose Co‐Transporter 2
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26036
Abstract: Type 2 Diabetes Mellitus (T2DM) and Alzheimer's disease (AD) are the two disorders which are known to share pertinent pathological and therapeutic links. Sodium glucose co‐transporter‐2 (SGLT2) and Acetylcholinesterase (AChE) are established inhibition targets for… read more here.
Keywords: sodium glucose; glucose transporter; diabetic drugs; anti diabetic ... See more keywords
Anti-diabetic drugs and sarcopenia: emerging links, mechanistic insights, and clinical implications.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.12838
Abstract: Sarcopenia, characterized by loss of skeletal muscle mass, quality, and strength, has become a common hallmark of ageing and many chronic diseases. Diabetes mellitus patients have a higher prevalence of sarcopenia, which greatly aggravates the… read more here.
Keywords: sarcopenia; diabetic drugs; clinical implications; muscle mass ... See more keywords
Impact of currently used anti-diabetic drugs on myoendothelial communication.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2018.11.002
Abstract: Diabetes is associated with a high risk of cardiovascular complications and ideally anti-diabetic drugs should not only reduce metabolic abnormalities but also reduce the negative impact of diabetes on vascular function; however, lowering blood glucose… read more here.
Keywords: impact currently; used anti; currently used; diabetic drugs ... See more keywords
Anti-diabetic drugs and NASH: from current options to promising perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2021.1951701
Abstract: ABSTRACT Introduction: Accumulating evidence supports a bidirectional association between nonalcoholic steatohepatitis (NASH) and type 2 diabetes (T2D). There is a clinical challenge to consider pharmaceutical strategies targeting the metabolic dysfunction common to NASH and T2D… read more here.
Keywords: current options; diabetic drugs; anti diabetic; nash current ... See more keywords
Comparative effectiveness of anti-diabetic drugs in morbidity and mortality of breast cancer in diabetic patients: A network meta-analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e24330
Abstract: e24330Background: Different anti-diabetic drugs may modify breast cancer (BC) morbidity and mortality in diabetic patients. We aimed to examine mortality and mortality of BC using a network meta-an... read more here.
Keywords: diabetic drugs; breast cancer; mortality; diabetic patients ... See more keywords
Genetic Variation in Targets of Anti-diabetic Drugs and Alzheimer Disease Risk: A Mendelian Randomization Study.
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000200771
Abstract: BACKGROUND AND OBJECTIVES Previous studies have highlighted anti-diabetic drugs as repurposing candidates for Alzheimer´s disease (AD), but the disease-modifying effects are still unclear. METHODS A two-sample Mendelian randomization (MR) study design was applied to examine… read more here.
Keywords: genetic variation; diabetic drugs; disease; anti diabetic ... See more keywords