A co-formulation of supramolecularly stabilized insulin and pramlintide enhances meal-time glucagon suppression in diabetic pigs
Sign Up to like & getrecommendations! Published in 2020 at "Nature biomedical engineering"
DOI: 10.1038/s41551-020-0555-4
Abstract: Treatment of patients with diabetes with insulin and pramlintide (an amylin analogue) is more effective than treatment with insulin only. However, because mixtures of insulin and pramlintide are unstable and have to be injected separately,… read more here.
Keywords: insulin; administration; suppression; glucagon ... See more keywords
Blocking RAGE improves wound healing in diabetic pigs
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DOI: 10.1111/iwj.13909
Abstract: Receptor for Advanced Glycated Endâproducts (RAGE) is highly expressed in diabetes and impairs wound healing. We proposed that administering an antibody that blocks RAGE will hasten the healing of dorsal wounds in diabetic pigs compared… read more here.
Keywords: healing diabetic; pig; wound healing; diabetic pigs ... See more keywords
The Inhibitory Effect of Regulatory T Cells on the Intimal Hyperplasia of Tissue-Engineered Blood Vessels in Diabetic Pigs
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.929867
Abstract: Severe inflammatory response and functional impairment of endothelial progenitor cells (EPCs) often lead to the implantation failure of EPC-captured tissue-engineered blood vessels (TEBVs) in diabetes. Regulatory T cells (Treg cells) are the most important inhibitory… read more here.
Keywords: regulatory cells; diabetic pigs; engineered blood; tissue engineered ... See more keywords