Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy
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DOI: 10.1038/ncomms15182
Abstract: Gene deletion-induced autophagy deficiency leads to neural tube defects (NTDs), similar to those in diabetic pregnancy. Here we report the key autophagy regulators modulated by diabetes in the murine developing neuroepithelium. Diabetes predominantly leads to… read more here.
Keywords: tube defects; diabetic pregnancy; suppresses autophagy; mir 129 ... See more keywords
Fetal growth regulation via insulin-like growth factor axis in normal and diabetic pregnancy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Perinatal Medicine"
DOI: 10.1515/jpm-2021-0510
Abstract: Abstract Objectives Diabetes mellitus (DM) in pregnancy and gestational diabetes remain a considerable cause of pregnancy complications, and fetal macrosomia is among them. Insulin, insulin-like growth factors (IGFs), and components of their signal-transduction axes belong… read more here.
Keywords: diabetic pregnancy; insulin like; growth; pregnancy ... See more keywords