Translocator protein 18 kDa ligand alleviates neointimal hyperplasia in the diabetic rat artery injury model via activating PKG
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2019.02.015
Abstract: Aims: The proliferation of VSMCs is the pathologic basis for intimal hyperplasia after angioplasty in diabetic patients. Translocator protein (TSPO), located in the outer mitochondrial membrane, has been found to regulate redox intermediate components in… read more here.
Keywords: proliferation; translocator protein; vsmc proliferation; migration ... See more keywords
Mitochondrial bound hexokinase type I in normal and streptozotocin diabetic rat retina.
Sign Up to like & getrecommendations! Published in 2020 at "Mitochondrion"
DOI: 10.1016/j.mito.2020.04.004
Abstract: Diabetic retinopathy is thought to be trigger by glucose- induced oxidative stress which leads to an increase of the mitochondrial permeability through opening the permeability transition pore (MTP). In several cell types, hexokinases interact with… read more here.
Keywords: mitochondrial bound; rat retinas; diabetic rat; bound hexokinase ... See more keywords
The effects of caffeic acid phenethyl ester on retina in a diabetic rat model
Sign Up to like & getrecommendations! Published in 2021 at "Cutaneous and Ocular Toxicology"
DOI: 10.1080/15569527.2021.1940196
Abstract: Abstract Purpose We aimed to investigate the effect of caffeic acid phenethyl ester (CAPE) on retinal apoptosis and oxidative stress parameters in streptozotocin (STZ) induced diabetic rat model. Methods This study included 3 groups; control,… read more here.
Keywords: stz cape; rat model; cape; diabetic rat ... See more keywords
Effects of Pravastatin on Type 1 Diabetic Rat Heart with or without Blood Glycemic Control
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Diabetes Research"
DOI: 10.1155/2018/1067853
Abstract: Although statins have been suggested to attenuate the progression of diabetic cardiomyopathy, its effect without glycemic control remains unclear. Therefore, we evaluated the effect of pravastatin on diabetic rat hearts according to glycemic control. Rats… read more here.
Keywords: heart; control; mmp; diabetic rat ... See more keywords
Superoxide dismutase 3 prevents early stage diabetic retinopathy in streptozotocin-induced diabetic rat model
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0262396
Abstract: Purpose To identify the effects of superoxide dismutase (SOD)3 on diabetes mellitus (DM)-induced retinal changes in a diabetic rat model. Methods Diabetic models were established by a single intraperitoneal injection of streptozotocin (STZ) in Sprague-Dawley… read more here.
Keywords: sod3; superoxide dismutase; group; diabetic rat ... See more keywords
Dapagliflozin Modulates the Fecal Microbiota in a Type 2 Diabetic Rat Model
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.00635
Abstract: Background: The gut microbiota is recognized as a major modulator of metabolic disorders such as type 2 diabetes. Dapagliflozin, sodium glucose cotransporter 2 inhibitors (SGLT2i), enhances renal glucose excretion, and lowers blood glucose levels. The… read more here.
Keywords: microbiota; microbiota type; type diabetic; fecal microbiota ... See more keywords
Puffball spores improve wound healing in a diabetic rat model
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.942549
Abstract: Persistent chronic oxidative stress is a primary pathogenic characteristics of diabetic foot ulcers. Puffball spores are a traditional Chinese medicine used to treat diabetic foot ulcers infections and bedsores. However, their effects against diabetic wounds… read more here.
Keywords: healing diabetic; wound healing; spores improve; puffball spores ... See more keywords
Exercise alleviates diabetic complications by inhibiting oxidative stress-mediated signaling cascade and mitochondrial metabolic stress in GK diabetic rat tissues
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.1052608
Abstract: Type 2 diabetes, obesity (referred to as “diabesity”), and metabolic syndrome associated with increased insulin resistance and/or decreased insulin sensitivity have been implicated with increased oxidative stress and inflammation, mitochondrial dysfunction, and alterations in energy… read more here.
Keywords: stress; metabolism; oxidative stress; energy ... See more keywords
Corinthian Currants Supplementation Restores Serum Polar Phenolic Compounds, Reduces IL-1beta, and Exerts Beneficial Effects on Gut Microbiota in the Streptozotocin-Induced Type-1 Diabetic Rat
Sign Up to like & getrecommendations! Published in 2023 at "Metabolites"
DOI: 10.3390/metabo13030415
Abstract: The present study aimed at investigating the possible benefits of a dietary intervention with Corinthian currants, a rich source of phenolic compounds, on type 1 diabetes (T1D) using the animal model of the streptozotocin-(STZ)-induced diabetic… read more here.
Keywords: corinthian currants; control; polar phenolic; diabetic rat ... See more keywords
Antioxidants Isolated from Elaeagnus umbellata (Thunb.) Protect against Bacterial Infections and Diabetes in Streptozotocin-Induced Diabetic Rat Model
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26154464
Abstract: The increase in resistance of microbes against conventional drugs is currently a hot issue, whereas diabetes is another main cause of mortalities encountered throughout the world after cancer and heart attacks. New drug sources in… read more here.
Keywords: streptozotocin induced; elaeagnus umbellata; induced diabetic; umbellata thunb ... See more keywords