Ticagrelor reduces myocardial cell injury induced by myocardial ischemia-reperfusion in diabetic rats by activating JAK2/STAT3.
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DOI: 10.1002/cbin.11940
Abstract: The treatment of diabetic patients with myocardial infarction is still full of challenges. Diabetes may exacerbate myocardial ischemia/reperfusion (I/R) injury. Ticagrelor alleviates I/R injury. However, the protective effects of ticagrelor on the diabetic myocardium following… read more here.
Keywords: diabetic rats; ticagrelor; myocardial ischemia; jak2 stat3 ... See more keywords
Protective effect of atorvastatin on oxidative stress in streptozotocin‐induced diabetic rats independently their lipid‐lowering effects
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22295
Abstract: In the present study, we investigate the effects of atorvastatin on the lipid profile, oxidative stress, and liver enzyme markers, and its protective activity against diabetic complications, in streptozotocin (STZ)‐induced diabetic rats. Fasting blood glucose… read more here.
Keywords: protective effect; induced diabetic; stress; diabetic rats ... See more keywords
Antidiabetic and neuroprotective effects of a novel repaglinide analog
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DOI: 10.1002/jbt.23125
Abstract: Repaglinide (RPG) is an oral insulin secretagogue used in the treatment of diabetes. In this study, a new RPG analog was synthesized. Its antidiabetic and neuroprotective effects on dorsal root ganglions (DRG) in streptozotocin (STZ)‐induced… read more here.
Keywords: diabetic rats; antidiabetic neuroprotective; neuroprotective effects; effects novel ... See more keywords
Cinnamic acid is beneficial to diabetic cardiomyopathy via its cardioprotective, anti‐inflammatory, anti‐dyslipidemia, and antidiabetic properties
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23215
Abstract: Diabetes‐related health issues are increasing day by day in public, and diabetic cardiomyopathy (DCM) is one serious issue among them. There is a lack of proper strategy to control and manage DCM. Here we are… read more here.
Keywords: diabetic rats; dcm; via cardioprotective; cinnamic acid ... See more keywords
The effect of melatonin on glycoprotein levels and oxidative liver injury in experimental diabetes
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DOI: 10.1002/jbt.23268
Abstract: In this present study, the duration of melatonin (Mel) administered to diabetic rats was prolonged so as to examine its effects on the biochemical liver parameters of diabetic rats. In the experiment, Male Sprague Dawley… read more here.
Keywords: diabetic rats; effect; mel; diabetic mel ... See more keywords
Alterations in lipid peroxidation, lipid profile, insulin sensitivity, and hepatic histopathological changes in diabetic rats following the treatment with Salvadora persica
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DOI: 10.1002/jcb.27649
Abstract: We examined the effects of various partitions of Salvadora persica extract on lipid profile (LP), lipid peroxidation, and insulin sensitivity (IS) of diabetic rats. The rats were divided into normal control, diabetic control (DC), standard,… read more here.
Keywords: diabetic rats; insulin; lipid profile; lipid peroxidation ... See more keywords
Preventing muscle wasting: pro‐insulin C‐peptide prevents loss in muscle mass in streptozotocin‐diabetic rats
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13210
Abstract: C‐peptide therapy exerts several positive actions on nerves, vasculature, smooth muscle relaxation, kidney function and bone. To date, the role of C‐peptide in preventing type 1 diabetes‐related muscle atrophy has not been investigated. Our aim… read more here.
Keywords: diabetic rats; preventing muscle; muscle wasting; wasting pro ... See more keywords
Gongronema latifolium Benth. leaf extract attenuates diabetes induced neuropathy via inhibition of cognitive, oxidative stress and inflammatory response.
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DOI: 10.1002/jsfa.10491
Abstract: BACKGROUND Gongronema latifolium (G. latifolium) Benth. leaf is traditionally used to treat diabetes mellitus (DM) and other diseases in Nigeria and West Africa. This study was performed to evaluate the neuroprotective effect of aqueous extract… read more here.
Keywords: oxidative stress; diabetic rats; leaf extract; latifolium ... See more keywords
Simultaneous determination of five alkaloids from Rauvolfia Vomitoria in rat plasma by LC-MS/MS: application to a comparative pharmacokinetic study in normal and Type 2 diabetic rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202000914
Abstract: Rauvolfia vomitoria is widely distributed in the tropical regions of Africa and Asia, and has been used in traditional folk medicine in China. Indole alkaloids were found to be major bioactive components, while the effects… read more here.
Keywords: simultaneous determination; medicine; determination five; rauvolfia vomitoria ... See more keywords
Dendrobium nobile Lindl polysaccharides improve testicular spermatogenic function in streptozotocin‐induced diabetic rats
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DOI: 10.1002/mrd.23556
Abstract: Dendrobium nobile Lindl polysaccharides (DNLP) exhibited various biological functions. This study aimed to investigate the protective effects of DNLP on testicular spermatogenic function in streptozotocin (STZ)‐induced diabetic rats in comparison with metformin. The blood glucose… read more here.
Keywords: diabetic rats; testicular spermatogenic; dendrobium nobile; induced diabetic ... See more keywords
Improvement of urethral dysfunction by 5‐HT1A receptor agonist NLX‐112 in diabetic rats
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DOI: 10.1002/nau.24993
Abstract: To examine the effects of the selective 5‐HT1A receptor agonist, NLX‐112, on urethral function in streptozotocin‐induced diabetic rats. read more here.
Keywords: diabetic rats; agonist nlx; ht1a receptor; nlx 112 ... See more keywords