Photothermal Controlled-Release Immunomodulatory Nanoplatform for Restoring Nerve Structure and Mechanical Nociception in Infectious Diabetic Ulcers.
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DOI: 10.1002/advs.202300339
Abstract: Infectious diabetic ulcers (IDU) require anti-infection, angiogenesis, and nerve regeneration therapy; however, the latter has received comparatively less research attention than the former two. In particular, there have been few reports on the recovery of… read more here.
Keywords: infectious diabetic; mechanical nociception; nociception; photothermal controlled ... See more keywords
In vitro glycation of a tissue‐engineered wound healing model to mimic diabetic ulcers
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DOI: 10.1002/bit.28359
Abstract: Diabetic foot ulcers are a major complication of diabetes that occurs following minor trauma. Diabetes‐induced hyperglycemia is a leading factor inducing ulcer formation and manifests notably through the accumulation of advanced glycation end‐products (AGEs) such… read more here.
Keywords: wound healing; glycation; model; healing model ... See more keywords
The global burden of diabetic wounds
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DOI: 10.1111/bjd.15254
Abstract: In a recent issue of the Annals of Medicine, Zhang et al. published a meta-analysis on diabetic ulcer prevalence based on 67 papers. In total, an impressive number of more than 800 000 subjects from… read more here.
Keywords: medicine; dermatology; prevalence; diabetic ulcers ... See more keywords
The effects of electrical stimulation on diabetic ulcers of foot and lower limb: A systematic review.
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DOI: 10.1111/iwj.13762
Abstract: Diabetic foot ulcer (DFU) is a life-threatening condition affecting a third of diabetic patients. Many adjuvant therapies aimed at improving the healing rate (HR) and accelerating healing time are currently under investigation. Electrical stimulation (ES)… read more here.
Keywords: diabetic ulcers; systematic review; electrical stimulation; effects electrical ... See more keywords
Characterisation of key biomarkers in diabetic ulcers via systems bioinformatics
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DOI: 10.1111/iwj.13900
Abstract: Diabetic ulcers (DUs) are characterised by a high incidence and disability rate. However, its pathogenesis remains elusive. Thus, a deep understanding of the underlying mechanisms for the pathogenesis of DUs has vital implications. The weighted… read more here.
Keywords: hub genes; characterisation key; ulcers via; biomarkers diabetic ... See more keywords
Metabolism-related biomarkers, molecular classification, and immune infiltration in diabetic ulcers with validation.
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DOI: 10.1111/iwj.14223
Abstract: Diabetes mellitus (DM) can lead to diabetic ulcers (DUs), which are the most severe complications. Due to the need for more accurate patient classifications and diagnostic models, treatment and management strategies for DU patients still… read more here.
Keywords: infiltration; classification; immune infiltration; metabolism related ... See more keywords
The effect of high‐voltage monophasic pulsed current on diabetic ulcers and their potential pathophysiologic factors: A systematic review and meta‐analysis
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DOI: 10.1111/wrr.13063
Abstract: The present review was conducted to determine the efficacy of high‐voltage monophasic pulsed current (HVMPC) in treating diabetic ulcers, assess its effect on skin lesions with each of the pathophysiologic factors potentially contributing to diabetic… read more here.
Keywords: high voltage; effect; monophasic pulsed; voltage monophasic ... See more keywords
Current and future outlook of loaded components in hydrogel composites for the treatment of chronic diabetic ulcers
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DOI: 10.3389/fbioe.2023.1077490
Abstract: Due to recalcitrant microangiopathy and chronic infection, traditional treatments do not easily produce satisfactory results for chronic diabetic ulcers. In recent years, due to the advantages of high biocompatibility and modifiability, an increasing number of… read more here.
Keywords: treatment chronic; hydrogel composites; treatment; chronic diabetic ... See more keywords
Oxidative Stress and Lipid Peroxidation: Prospective Associations Between Ferroptosis and Delayed Wound Healing in Diabetic Ulcers
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DOI: 10.3389/fcell.2022.898657
Abstract: Diabetic ulcers are one of the major complications of diabetes, and patients usually suffer from amputation and death due to delayed ulcer wound healing. Persistent inflammation and oxidative stress at the wound site are the… read more here.
Keywords: healing diabetic; lipid peroxidation; wound healing; oxidative stress ... See more keywords