A Multifunctional Pro‐Healing Zwitterionic Hydrogel for Simultaneous Optical Monitoring of pH and Glucose in Diabetic Wound Treatment
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DOI: 10.1002/adfm.201905493
Abstract: Diabetic ulcer is the most common kind of chronic wound worldwide. Though great efforts have been devoted, diabetic ulcer still remains as a challenge that requires constant monitoring and management. In this work, a multifunctional… read more here.
Keywords: wound; zwitterionic hydrogel; treatment; diabetic wound ... See more keywords
Bioinspired Intrinsic Versatile Hydrogel Fabricated by Amyloidal Toxin Simulant‐Based Nanofibrous Assemblies for Accelerated Diabetic Wound Healing
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DOI: 10.1002/adfm.202106705
Abstract: Persistent microbial infection and decreased neovascularization are common issues associated with diabetic wound treatment. Hydrogel dressings that offer intrinsic antibacterial and angiogenesis‐inducing may substantially avoid the use of antibiotics or angiogenic agents. Herein, a versatile… read more here.
Keywords: wound; versatile hydrogel; simulant; hydrogel fabricated ... See more keywords
Nanofiber Aerogels with Precision Macrochannels and LL‐37‐Mimic Peptides Synergistically Promote Diabetic Wound Healing
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DOI: 10.1002/adfm.202206936
Abstract: Fast healing of diabetic wounds remains a major clinical challenge. Herein, this study reports a strategy to combine nanofiber aerogels containing precision macrochannels and the LL‐37‐mimic peptide W379 for rapid diabetic wound healing. Nanofiber aerogels… read more here.
Keywords: precision macrochannels; nanofiber aerogels; macrochannels mimic; diabetic wound ... See more keywords
Bioinspired Multifunctional Black Phosphorus Hydrogel with Antibacterial and Antioxidant Properties: A Stepwise Countermeasure for Diabetic Skin Wound Healing
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DOI: 10.1002/adhm.202102791
Abstract: Cutaneous wound healing, especially diabetic wound healing, is a common clinical challenge. Reactive oxygen species (ROS) and bacterial infection are two major detrimental states that induce oxidative stress and inflammatory responses and impede angiogenesis and… read more here.
Keywords: wound healing; hydrogel; antibacterial antioxidant; diabetic wound ... See more keywords
Injectable Dual‐Dynamic‐Bond Cross‐Linked Hydrogel for Highly Efficient Infected Diabetic Wound Healing
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DOI: 10.1002/adhm.202200516
Abstract: Diabetic wound is a significant challenge for clinical treatment with high morbidity and mortality. Plenty of hydrogels with good biocompatibility have been widely used in diabetic wound healing. However, most of them cannot be directly… read more here.
Keywords: wound healing; cross linked; dual dynamic; cross ... See more keywords
Sponge‐Like Macroporous Hydrogel with Antibacterial and ROS Scavenging Capabilities for Diabetic Wound Regeneration (Adv. Healthcare Mater. 20/2022)
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DOI: 10.1002/adhm.202200717
Abstract: Hydrogels with soft and wet properties have been intensively investigated for chronic disease tissue repair. Nevertheless, tissue engineering hydrogels containing high water content are often simultaneously suffered from low porous size and low water-resistant capacities,… read more here.
Keywords: sponge like; water; ros scavenging; macro porous ... See more keywords
Biodegradable and Antioxidant DNA Hydrogel as a Cytokine Delivery System for Diabetic Wound Healing
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DOI: 10.1002/adhm.202200782
Abstract: Impaired diabetic wound healing is associated with the persistence of chronic inflammation and excessive oxidative stress, which has become one of the most serious clinical challenges. Wound dressings with anti‐inflammatory and reactive oxygen species (ROS)‐scavenging… read more here.
Keywords: wound; wound healing; diabetic wound; biodegradable antioxidant ... See more keywords
A Nanozyme‐Immobilized Hydrogel with Endogenous ROS‐Scavenging and Oxygen Generation Abilities for Significantly Promoting Oxidative Diabetic Wound Healing
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DOI: 10.1002/adhm.202201524
Abstract: Non‐healing wound is a common complication of diabetic patients associated with high morbidity and mortality. Engineered therapeutic hydrogels have enviable advantages in tissue regeneration, however, they are suboptimal for the healing of diabetic wounds characterized… read more here.
Keywords: wound; wound healing; diabetic wounds; diabetic wound ... See more keywords
Dapagliflozin‐Loaded Exosome Mimetics Facilitate Diabetic Wound Healing by HIF‐1α‐Mediated Enhancement of Angiogenesis
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DOI: 10.1002/adhm.202202751
Abstract: Angiogenesis plays a critical role in diabetic wound healing. However, no effective strategies have been developed to target endothelial cells (ECs) to facilitate diabetic wound healing. Dapagliflozin (DA) as a sodium‐glucose linked transporter 2 (SGLT2)… read more here.
Keywords: wound healing; facilitate diabetic; diabetic wound; angiogenesis ... See more keywords
A glucose-responsive antioxidant hydrogel accelerates diabetic wound healing.
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DOI: 10.1002/adhm.202300074
Abstract: Diabetic complications can be ameliorated by inhibiting excessive oxidative stress with antioxidants. To enhance therapeutic intervention, it is crucial to develop intelligent scaffolds for efficient delivery of antioxidants to diabetic wounds. In this study, we… read more here.
Keywords: wound healing; antioxidant hydrogel; hydrogel; diabetic wound ... See more keywords
Immunoregulation in Diabetic Wound Repair with a Photoenhanced Glycyrrhizic Acid Hydrogel Scaffold
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DOI: 10.1002/adma.202200521
Abstract: M1 macrophage accumulation and excessive inflammation are commonly encountered issues in diabetic wounds and can fail in the healing process. Hence, hydrogel dressings with immunoregulatory capacity have great promise in the clinical practice of diabetic… read more here.
Keywords: hydrogel; diabetic wound; wound repair; glycyrrhizic acid ... See more keywords