A Nanozyme‐Immobilized Hydrogel with Endogenous ROS‐Scavenging and Oxygen Generation Abilities for Significantly Promoting Oxidative Diabetic Wound Healing
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201524
Abstract: Non‐healing wound is a common complication of diabetic patients associated with high morbidity and mortality. Engineered therapeutic hydrogels have enviable advantages in tissue regeneration, however, they are suboptimal for the healing of diabetic wounds characterized… read more here.
Keywords: wound; wound healing; diabetic wounds; diabetic wound ... See more keywords
Erratum: Human Wharton's Jelly Stem Cells and Its Conditioned Medium Enhance Healing of Excisional and Diabetic Wounds
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26081
Abstract: Wound healing is a major problem in diabetic patients and current treatments have met with limited success. We evaluated the treatment of excisional and diabetic wounds using a stem cell isolated from the human umbilical… read more here.
Keywords: conditioned medium; excisional diabetic; wharton jelly; hwjsc ... See more keywords
ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120286
Abstract: Bacterial infection has been a great threat to dermal wounds, especially to difficult-to-heal diabetic wounds. It is known that reactive oxygen species (ROS) generated by wounds or bacterial infection could further impede wound healing. Here,… read more here.
Keywords: bacterial infection; hydrogel; diabetic wounds; scavenging hydrogel ... See more keywords
Hyaluronic acid functionalized nanoparticles for simultaneous delivery of curcumin and resveratrol for management of chronic diabetic wounds: Fabrication, characterization, stability and in vitro release kinetics
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101747
Abstract: Abstract Owing to their complex pathophysiology, diabetic wounds (DWs) pose serious challenges to current pharmacological modalities, eventually leading to high rate of amputation of lower extremities. This study aims to design novel hyaluronic acid (HA)-functionalized… read more here.
Keywords: acid functionalized; delivery; delivery curcumin; diabetic wounds ... See more keywords
Blood-Glucose-Depleting Hydrogel Dressing as an Activatable Photothermal/Chemodynamic Antibacterial Agent for Healing Diabetic Wounds.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c03786
Abstract: Poorly healing and nonhealing diabetic wounds are challenging to treat as the rapid growth of bacteria due to the high local glucose content can lead to persistent inflammation and poor angiogenesis. Herein, a smart hydrogel… read more here.
Keywords: diabetic wounds; hydrogel dressing; blood glucose; glucose depleting ... See more keywords
Ionic liquid functionalized injectable and conductive hyaluronic acid hydrogels for the efficient repair of diabetic wounds under electrical stimulation.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00026a
Abstract: The treatment and care of diabetic wounds remains a global challenge due to the high rates of amputation, recurrence, and mortality. It has been proven that electrical stimulation has a positive effect on promoting diabetic… read more here.
Keywords: ionic liquid; electrical stimulation; diabetic wounds; hyaluronic acid ... See more keywords
A core/shell nanogenerator achieving pH-responsive nitric oxide release for treatment of infected diabetic wounds.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr03704a
Abstract: Nitric oxide is critical for eliminating infection and promoting regeneration in diabetic wounds. However, clinical uses of nitric oxide are limited by its high activity and lack of specificity in targeting infections. Herein, we develop… read more here.
Keywords: nanogenerator; core shell; diabetic wounds; nitric oxide ... See more keywords
Nanoenzyme-chitosan hydrogel complex with cascade catalytic and self-reinforced antibacterial performance for accelerated healing of diabetic wounds.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr04171e
Abstract: The significant disability and fatality rate of diabetes chronic wounds necessitates the development of efficient diabetic wound healing techniques. The present oxygen treatments for wound healing is restricted by issues such as poor penetration, inadequate… read more here.
Keywords: wound healing; hydrogel complex; hydrogel; diabetic wounds ... See more keywords
Topical Naltrexone Is a Safe and Effective Alternative to Standard Treatment of Diabetic Wounds.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in wound care"
DOI: 10.1089/wound.2016.0725
Abstract: Objective: Diabetes affects more than 29 million individuals in the United States, resulting in healthcare costs approaching $245 billion. Approximately 15% of these individuals will develop a chronic, non-healing foot ulcer (diabetic foot ulcer [DFU])… read more here.
Keywords: effective alternative; treatment diabetic; treatment; growth factor ... See more keywords
Efficacy and safety of chitosan‐based bio‐compatible dressing versus nanosilver (ActicoatTM) dressing in treatment of recalcitrant diabetic wounds: A randomized clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic Therapy"
DOI: 10.1111/dth.15682
Abstract: Chitosan has a biocompatible, biodegradable, and nontoxic nature. The effectiveness of Nano‐chitosan films in the field of wound healing has been confirmed previously. The aim of this study was to compare the clinical efficacy and… read more here.
Keywords: acticoattm dressing; diabetic wounds; nanosilver acticoattm; efficacy safety ... See more keywords
Bacillus subtilis WB800N alleviates diabetic wounds in mice by regulating gut microbiota homeostasis and TLR2
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Microbiology"
DOI: 10.1111/jam.15547
Abstract: This study aims to investigate the effect of Bacillus subtilis WB800N on diabetic wounds. read more here.
Keywords: subtilis wb800n; alleviates diabetic; bacillus subtilis; wb800n alleviates ... See more keywords