Articles with "diadenosine triphosphate" as a keyword



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Chemical proteomics reveals interactors of the alarmone diadenosine triphosphate in the cancer cell line H1299 †

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Published in 2022 at "Journal of Peptide Science"

DOI: 10.1002/psc.3458

Abstract: Intracellular dinucleoside polyphosphates (NpnNs) have been known for decades but the functional role remains enigmatic. Diadenosine triphosphate (Ap3A) is one of the most prominent examples, and its intercellular concentration was shown to increase upon cellular… read more here.

Keywords: cell; diadenosine triphosphate; cell line; chemical proteomics ... See more keywords
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Chemical proteomic profiling reveals protein interactors of the alarmones diadenosine triphosphate and tetraphosphate

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Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-26075-4

Abstract: The nucleotides diadenosine triphosphate (Ap3A) and diadenosine tetraphosphate (Ap4A) are formed in prokaryotic and eukaryotic cells. Since their concentrations increase significantly upon cellular stress, they are considered to be alarmones triggering stress adaptive processes. However,… read more here.

Keywords: profiling reveals; protein interactors; reveals protein; proteomic profiling ... See more keywords