T‐cell clonality testing for the diagnosis of T‐cell large granular lymphocytic leukemia: Are we identifying pathology or incidental clones?
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.13949
Abstract: T‐cell clonality testing by T‐cell receptor (TCR) gene rearrangement is key to the diagnosis of T‐cell lymphoproliferative disorders such as T‐cell large granular lymphocytic (T‐LGL) leukemia. Benign clonal T‐cell expansions, however, are commonly found in… read more here.
Keywords: cell; cell clonality; pathology; diagnosis cell ... See more keywords
Molecular Diagnosis of T-cell Lymphoma: A correlative study of PCR-based T-cell clonality assessment and targeted NGS.
Sign Up to like & getrecommendations! Published in 2021 at "Blood advances"
DOI: 10.1182/bloodadvances.2021005249
Abstract: Immunomorphological diagnosis of T-cell lymphomas (TCL) may be challenging, especially on needle biopsies. Multiplex polymerase chain reaction (PCR) assays to assess T-cell receptor (TCR) gene rearrangements are now widely used to detect T-cell clones and… read more here.
Keywords: diagnosis cell; diagnosis; cell clonality; pcr ... See more keywords