Circulating miRNA landscape identifies miR-1246 as promising diagnostic biomarker in high-grade serous ovarian carcinoma: A validation across two independent cohorts.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2016.12.017
Abstract: High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecologic neoplasm, with five-year survival rate below 30%. Early disease detection is of utmost importance to improve HGSOC cure rate. Sera from 168 HGSOC patients and… read more here.
Keywords: hgsoc; validation; high grade; mir 1246 ... See more keywords
Circulating mitochondria DNA, a non-invasive cancer diagnostic biomarker candidate.
Sign Up to like & getrecommendations! Published in 2018 at "Mitochondrion"
DOI: 10.1016/j.mito.2018.12.003
Abstract: The mitochondria are defined by their unique structure and cellular functions which includes energy production, metabolic regulation, apoptosis, calcium homeostasis, cell proliferation, cell motility and transport as well as free radical generation. Recent advances geared… read more here.
Keywords: circulating mitochondria; mitochondria dna; non invasive; cancer ... See more keywords
Platelet MicroRNA-484 as a Novel Diagnostic Biomarker for Acute Coronary Syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac102
Abstract: OBJECTIVE Platelet microRNAs (miRs) have been indicated as a diagnostic biomarker in various diseases, including acute coronary syndrome (ACS). This study aimed to investigate the expression of miR-223-5p, miR-126-5p, miR-484, and miR-130a-3p in individuals with… read more here.
Keywords: acute coronary; expression; diagnostic biomarker; mir ... See more keywords
The screening of diagnostic biomarker microRNA in first-trimester maternal plasma for Down syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000028495
Abstract: Abstract Background: The trisomy of human chromosome 21 causes Down syndrome (DS), sometimes known as congenital folly's syndrome. The survivors show apparent mental impairment, unusual facial traits, growth and development abnormalities, and various deformities, with… read more here.
Keywords: trimester maternal; maternal plasma; first trimester; diagnostic biomarker ... See more keywords
Serum miR‐92a‐1 is a novel diagnostic biomarker for colorectal cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15282
Abstract: Colorectal cancer (CRC) is one of the most common cancers worldwide, with high mortality. Abnormally expressed microRNAs (miRNAs) are considered novel biomarkers in cancer diagnosis. The aim of this study was to investigate the diagnostic… read more here.
Keywords: diagnostic biomarker; colorectal cancer; mir 92a; serum mir ... See more keywords
LCN2 is a new diagnostic biomarker and potential therapeutic target in idiopathic short stature
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17408
Abstract: Idiopathic short stature (ISS) is the most common paediatric endocrine disease. However, the underlying pathology of ISS remains unclear. Currently, there are no effective diagnostic markers or therapeutic strategies available for ISS. In this study,… read more here.
Keywords: new diagnostic; lcn2 new; stature; short stature ... See more keywords
Economic and Diagnostic Biomarker Tests of Neonatal Sepsis: A Prospective Study from a Tertiary Care Hospital in a Low-Income Country
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/5166380
Abstract: Background Neonatal sepsis is a leading cause of morbidity and mortality in low-and middle-income countries (LMICs). There are several sophisticated biomarkers; however, they are still insufficient in precision. In this perspective, our study aims to… read more here.
Keywords: sepsis; biomarker; neonatal sepsis; biomarker tests ... See more keywords
Serum miR-128 Serves as a Potential Diagnostic Biomarker for Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s290925
Abstract: Background Although numerous microRNAs (miRNAs) have been discovered to participate in the progression of Alzheimer’s disease (AD), they are still difficult to apply in clinical work. Thus, the identification of novel miRNAs and clarification of… read more here.
Keywords: mir 128; alzheimer disease; diagnostic biomarker; serum mir ... See more keywords
miR-139-5p and miR-451a as a Diagnostic Biomarker in LUSC
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s402750
Abstract: Background Lung squamous cell carcinoma (LUSC) is a type of lung cancer that originates from segmental or subsegmental bronchial mucosa. There is evidence that miRNA plays an important role in the occurrence and progression of… read more here.
Keywords: mir 139; diagnostic biomarker; 451a diagnostic; 139 mir ... See more keywords
APOC1 as a novel diagnostic biomarker for DN based on machine learning algorithms and experiment
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1102634
Abstract: Introduction Diabetic nephropathy is the leading cause of end-stage renal disease, which imposes a huge economic burden on individuals and society, but effective and reliable diagnostic markers are still not available. Methods Differentially expressed genes… read more here.
Keywords: novel diagnostic; apoc1 novel; expression; diagnostic biomarker ... See more keywords
Extracellular vesicles: A new diagnostic biomarker and targeted drug in osteosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1002742
Abstract: Osteosarcoma (OS) is a primary bone cancer that is highly prevalent among adolescents and adults below the age of 20 years. The prognostic outcome of metastatic OS or relapse is extremely poor; thus, developing new… read more here.
Keywords: new diagnostic; osteosarcoma; extracellular vesicles; biomarker targeted ... See more keywords