CKAP4 in Extracellular Vesicle‐Derived From Podocyte Serves as a Non‐Invasive Diagnostic Biomarker for Diabetic Nephropathy and Promotes Vascular Calcification
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70208
Abstract: ABSTRACT Reliable non‐invasive biomarkers for early detection of diabetic nephropathy (DN), a leading cause of chronic kidney disease, remain limited. In this study, we isolate urinary extracellular vesicles (uEVs) using wheat germ agglutinin (WGA)‐conjugated magnetic… read more here.
Keywords: diagnostic biomarker; vascular calcification; ckap4; diabetic nephropathy ... See more keywords
MicroRNA mmu-miR-511-5p: A promising Diagnostic Biomarker in Experimental Toxoplasmosis Using Different Strains and Infective Doses in Mice with Different Immune States Before and After Treatment
Sign Up to like & getrecommendations! Published in 2024 at "Acta Parasitologica"
DOI: 10.1007/s11686-024-00851-w
Abstract: Searching for a novel early diagnostic biomarker for toxoplasmosis, real-time-PCR was currently used to measure the serum mmu-miR-511-5p level in male Swiss-albino mice infected with either; ME49 or RH Toxoplasma gondii (T. gondii) strains. Three… read more here.
Keywords: mir 511; mmu mir; treatment; diagnostic biomarker ... See more keywords
Circulating miRNA landscape identifies miR-1246 as promising diagnostic biomarker in high-grade serous ovarian carcinoma: A validation across two independent cohorts.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2016.12.017
Abstract: High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecologic neoplasm, with five-year survival rate below 30%. Early disease detection is of utmost importance to improve HGSOC cure rate. Sera from 168 HGSOC patients and… read more here.
Keywords: hgsoc; validation; high grade; mir 1246 ... See more keywords
Circulating mitochondria DNA, a non-invasive cancer diagnostic biomarker candidate.
Sign Up to like & getrecommendations! Published in 2018 at "Mitochondrion"
DOI: 10.1016/j.mito.2018.12.003
Abstract: The mitochondria are defined by their unique structure and cellular functions which includes energy production, metabolic regulation, apoptosis, calcium homeostasis, cell proliferation, cell motility and transport as well as free radical generation. Recent advances geared… read more here.
Keywords: circulating mitochondria; mitochondria dna; non invasive; cancer ... See more keywords
Circulating CHI3L1 autoantibodies serve as a diagnostic biomarker in patients with obstructive sleep apnea
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-11537-2
Abstract: While polysomnography (PSG) is the gold standard for diagnosing obstructive sleep apnea (OSA), its limited availability means that many patients remain undiagnosed. This study seeks to evaluate whether CHI3L1-Ab could serve as a diagnostic biomarker… read more here.
Keywords: diagnostic biomarker; chi3l1; obstructive sleep; sleep apnea ... See more keywords
Platelet MicroRNA-484 as a Novel Diagnostic Biomarker for Acute Coronary Syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac102
Abstract: OBJECTIVE Platelet microRNAs (miRs) have been indicated as a diagnostic biomarker in various diseases, including acute coronary syndrome (ACS). This study aimed to investigate the expression of miR-223-5p, miR-126-5p, miR-484, and miR-130a-3p in individuals with… read more here.
Keywords: acute coronary; expression; diagnostic biomarker; mir ... See more keywords
The screening of diagnostic biomarker microRNA in first-trimester maternal plasma for Down syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000028495
Abstract: Abstract Background: The trisomy of human chromosome 21 causes Down syndrome (DS), sometimes known as congenital folly's syndrome. The survivors show apparent mental impairment, unusual facial traits, growth and development abnormalities, and various deformities, with… read more here.
Keywords: trimester maternal; maternal plasma; first trimester; diagnostic biomarker ... See more keywords
ZNF143 as a diagnostic biomarker: Insights from gene expression and immune cell infiltration in COPD and asthma
Sign Up to like & getrecommendations! Published in 2025 at "Medicine"
DOI: 10.1097/md.0000000000045317
Abstract: Chronic obstructive pulmonary disease (COPD) and asthma are common and serious respiratory diseases worldwide. Their clinical overlap and lack of specificity in current biomarkers pose a great diagnostic challenge for early diagnosis. To address this… read more here.
Keywords: copd asthma; diagnostic biomarker; copd; cell ... See more keywords
MicroRNA‐199a‐5p may be a diagnostic biomarker of primary ITP
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DOI: 10.1111/bjh.19987
Abstract: There is no diagnostic test for primary immune thrombocytopenia (ITP). Certain microRNAs have shown to have diagnostic potential in ITP. We validated 12 microRNAs identified from two previous studies to find a diagnostic biomarker. The… read more here.
Keywords: diagnostic biomarker; primary itp; mir 199a; mir ... See more keywords
Serum miR‐92a‐1 is a novel diagnostic biomarker for colorectal cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15282
Abstract: Colorectal cancer (CRC) is one of the most common cancers worldwide, with high mortality. Abnormally expressed microRNAs (miRNAs) are considered novel biomarkers in cancer diagnosis. The aim of this study was to investigate the diagnostic… read more here.
Keywords: diagnostic biomarker; colorectal cancer; mir 92a; serum mir ... See more keywords
LCN2 is a new diagnostic biomarker and potential therapeutic target in idiopathic short stature
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17408
Abstract: Idiopathic short stature (ISS) is the most common paediatric endocrine disease. However, the underlying pathology of ISS remains unclear. Currently, there are no effective diagnostic markers or therapeutic strategies available for ISS. In this study,… read more here.
Keywords: new diagnostic; lcn2 new; stature; short stature ... See more keywords