MicroRNAs and exosomes in depression: Potential diagnostic biomarkers
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26599
Abstract: Depression is known as one of important psychiatric disorders which could be associated with disability among various populations. Diagnostic and statistical manual of mental disorders, 4th edition (DSM‐IV) and international statistical classification of diseases and… read more here.
Keywords: depression; micrornas exosomes; diagnostic biomarkers; could used ... See more keywords
Identification and Validation of Potential Diagnostic Biomarkers for Pulmonary Arterial Hypertension Based on Gene Expression Profiling
Sign Up to like & getrecommendations! Published in 2025 at "Pulmonary Circulation"
DOI: 10.1002/pul2.70207
Abstract: ABSTRACT Pulmonary arterial hypertension (PAH) is a life‐threatening condition characterized by elevated pulmonary vascular resistance. Despite recent advances, early diagnosis remains challenging due to nonspecific symptoms. By utilizing RNA sequencing (RNA‐seq) data from the GEO… read more here.
Keywords: arterial hypertension; potential diagnostic; validation; pulmonary arterial ... See more keywords
Candidate diagnostic biomarkers for neurodevelopmental disorders in children and adolescents: a systematic review
Sign Up to like & getrecommendations! Published in 2023 at "World Psychiatry"
DOI: 10.1002/wps.21037
Abstract: Neurodevelopmental disorders – including attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder, communication disorders, intellectual disability, motor disorders, specific learning disorders, and tic disorders – manifest themselves early in development. Valid, reliable and broadly usable biomarkers supporting… read more here.
Keywords: neurodevelopmental disorders; candidate diagnostic; disorders children; systematic review ... See more keywords
Machine learning to identify immune-related biomarkers of rheumatoid arthritis based on WGCNA network
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-05960-9
Abstract: This study was designed to identify the potential diagnostic biomarkers of rheumatoid arthritis (RA) and to explore the potential pathological relevance of immune cell infiltration in this disease. Three previously published datasets containing gene expression… read more here.
Keywords: machine; diagnostic biomarkers; infiltration; hub genes ... See more keywords
Identification of Novel Diagnostic Biomarkers in Breast Cancer Using Targeted Metabolomic Profiling.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical breast cancer"
DOI: 10.1016/j.clbc.2020.09.006
Abstract: INTRODUCTION Breast cancer (BC) is the most common cancer in women, with a high disease burden, especially in the advanced disease stages. Our study investigated the metabolomic profile of breast cancer patients' serum with the… read more here.
Keywords: targeted metabolomic; diagnostic biomarkers; breast cancer; sensitivity specificity ... See more keywords
Comprehensive Analysis of mRNA Expression Profiling and Identification of Potential Diagnostic Biomarkers in Coronary Artery Disease
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c03171
Abstract: The aim of this study is to investigate mRNA expression profiling by RNA sequencing (RNA-seq) in patients with coronary artery disease (CAD) and validate differentially expressed genes (DEGs) as novel biomarkers for CAD. Transcriptome-wide mRNA… read more here.
Keywords: diagnostic biomarkers; analysis; coronary artery; expression ... See more keywords
Proteomic analysis of plasma and duodenal tissue in celiac disease patients reveals potential noninvasive diagnostic biomarkers
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-80391-5
Abstract: The pathogenesis of celiac disease (CeD) remains incompletely understood. Traditional diagnostic techniques for CeD include serological testing and endoscopic examination; however, they have limitations. Therefore, there is a need to identify novel noninvasive biomarkers for… read more here.
Keywords: analysis; celiac disease; noninvasive diagnostic; plasma ... See more keywords
Identification of diagnostic biomarkers and dissecting immune microenvironment with crosstalk genes in the POAG and COVID-19 nexus
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-10656-0
Abstract: An underlying association between primary open-angle glaucoma (POAG) and COVID-19 has been hypothesized, but the causal link and shared mechanisms remain unclear. This study integrates epidemiological and bioinformatics approaches to investigate their relationship, aiming to… read more here.
Keywords: crosstalk genes; poag covid; covid; immune microenvironment ... See more keywords
Identification and validation of the inflammatory response-related LncRNAs as diagnostic biomarkers for acute ischemic stroke
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-98101-0
Abstract: Ischemic stroke is one of the leading causes of deaths and disability, which is linked to inflammation. In this study, we aimed to identify inflammation-related lncRNAs as diagnostic biomarkers of acute ischemic stroke (AIS). A… read more here.
Keywords: related lncrnas; lncrnas diagnostic; ischemic stroke; biomarkers acute ... See more keywords
Identification of potential M2 macrophage-associated diagnostic biomarkers in coronary artery disease
Sign Up to like & getrecommendations! Published in 2022 at "Bioscience Reports"
DOI: 10.1042/bsr20221394
Abstract: Abstract Background: M2 macrophages have been reported to be important in the progression of coronary artery disease (CAD). Thus, the present study aims at exploring the diagnostic value of M2 macrophage-associated genes in CAD. Methods:… read more here.
Keywords: macrophage associated; artery disease; diagnostic biomarkers; associated diagnostic ... See more keywords
Identification of MORN3 and LLGL2 as novel diagnostic biomarkers for latent tuberculosis infection using machine learning strategies and experimental verification
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Medicine"
DOI: 10.1080/07853890.2024.2380797
Abstract: Abstract Background Current diagnostic methods cannot effectively distinguish between latent tuberculosis infection (LTBI) and active tuberculosis (ATB). This study aims to explore novel non-invasive diagnostic biomarkers for LTBI and to elucidate possible molecular mechanisms of… read more here.
Keywords: morn3 llgl2; tuberculosis; machine learning; infection ... See more keywords