Tumor microenvironment differences between diagnostic and relapsed classic Hodgkin lymphoma revealed by scRNA-seq.
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DOI: 10.1182/bloodadvances.2025017107
Abstract: Key Points • Naïve B cells expressing LGALS9 (galectin-9) are distinctly increased in early-relapse CHL compared to diagnostic and late-relapse samples.• Galectin-9–positive naïve B cells engage with TIM-3+ T cells, potentially contributing to an immunosuppressive… read more here.
Keywords: microenvironment differences; classic hodgkin; tumor microenvironment; diagnostic relapsed ... See more keywords