The Clinicopathologic Spectrum of Rosai–Dorfman–Destombes Disease in Adults: An Analysis of 16 Cases
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Haematology"
DOI: 10.1111/ejh.70018
Abstract: Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytic proliferation with protean clinical manifestations, resulting from the accumulation of activated histiocytes within nodal and extra‐nodal tissues. The diagnosis can be missed, particularly when biopsies are obtained from… read more here.
Keywords: diagnosis; dorfman destombes; destombes disease; rdd ... See more keywords
Utility of Retrospective Molecular Analysis in Diagnostically Challenging Mesenchymal Neoplasms.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of surgical pathology"
DOI: 10.1177/10668969231157783
Abstract: Introduction: Molecular analysis plays a growing role in the diagnosis of mesenchymal neoplasms. The aim of this study was to retrospectively apply broad, multiplex molecular assays (a solid tumor targeted next-generation sequencing [NGS]) assay and… read more here.
Keywords: diagnostically challenging; mesenchymal neoplasms; molecular analysis; challenging mesenchymal ... See more keywords
A Comparative Study Between Copy Number Alterations and PRAME Immunohistochemical Pilot Study in Challenging Melanocytic Lesions
Sign Up to like & getrecommendations! Published in 2025 at "Cancers"
DOI: 10.3390/cancers17071218
Abstract: Simple Summary Melanoma is a significant public health concern due to its rising incidence and mortality. While most melanocytic lesions can be readily classified as benign nevi or malignant melanoma, diagnostically challenging lesions remain difficult… read more here.
Keywords: study copy; study; comparative study; diagnostically challenging ... See more keywords
Diagnostically Challenging Subtypes of Invasive Lobular Carcinomas: How to Avoid Potential Diagnostic Pitfalls
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12112658
Abstract: Invasive lobular carcinoma is the most common special breast carcinoma subtype, with unique morphological (discohesive cells, single-cell files, targetoid pattern) and immunohistochemical (loss of E-cadherin and β-catenin staining) features. Moreover, ILC displays a poor response… read more here.
Keywords: diagnostically challenging; diagnostic pitfalls; invasive lobular; lobular carcinoma ... See more keywords