N-Substituted cyanacetohydrazides in the synthesis of 3,3-dialkyl-1,2,3,4-tetrahydroisoquinolines by Ritter reaction
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DOI: 10.1007/s10593-017-2180-z
Abstract: Cyanacetohydrazide, protected at the nitrogen atom of hydrazide group, underwent cyclocondensation by Ritter reaction with 3,3-dialkylbenzylcarbinols, forming 3,3-dialkyl-1,2,3,4-tetrahydroisoquinolines. The reagents used for the protection of hydrazide group were benzaldehyde, benzoyl chloride, phenyl isocyanate, and phenyl… read more here.
Keywords: synthesis dialkyl; ritter reaction; dialkyl tetrahydroisoquinolines; cyanacetohydrazides synthesis ... See more keywords