Articles with "dialkylated oxindoles" as a keyword



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Synthesis of 3,3-Dialkylated Oxindoles by Oxidative Radical 1,2-Alkylarylation of α,β-Unsaturated Amides

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Published in 2017 at "Synlett"

DOI: 10.1055/s-0036-1588754

Abstract: 3,3-Dialkylated oxindoles (1,3-dihydro-2 H -indol-2-ones), particularly those containing C3 quaternary stereogenic centers, occupy an important place in organic synthesis and drug discovery. The radical 1,2-alkylarylation of activated olefins with alkyl radicals has emerged as the… read more here.

Keywords: radical alkylarylation; unsaturated amides; dialkylated oxindoles; synthesis ... See more keywords