A comprehensive understanding about the pharmacological effect of diallyl disulfide other than its anti-carcinogenic activities.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173803
Abstract: Diallyl disulfide (DADS), an oil-soluble sulfur compound that is responsible for the biological effects of garlic, displays numerous biological activities, among which its anti-cancer activities are the most famous ones. In recent years, the pharmacological… read more here.
Keywords: diallyl disulfide; effects dads; carcinogenic activities; anti carcinogenic ... See more keywords
Effect of diallyl disulfide on physiological performance of Ephestia kuehniella Zeller (Lepidoptera: Pyralidae)
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Phytopathology and Plant Protection"
DOI: 10.1080/03235408.2016.1253252
Abstract: Abstract Ephestia kuehniella Zeller is a key pest by severe deficiencies on quantity and quality of stored products. Due to concerns made by synthetic insecticides, use of natural products (like botanical insecticides) is of great… read more here.
Keywords: effect; ephestia kuehniella; kuehniella zeller; kuehniella ... See more keywords
Diallyl disulfide down‐regulates calreticulin and promotes C/EBPα expression in differentiation of human leukaemia cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13904
Abstract: Diallyl disulfide (DADS), the main active component of the cancer fighting allyl sulfides found in garlic, has shown potential as a therapeutic agent in various cancers. Previous studies showed DADS induction of HL‐60 cell differentiation… read more here.
Keywords: expression; differentiation; ebp expression; diallyl disulfide ... See more keywords
VALIDATION AND ANALYSIS OF DIALLYL DISULFIDE AND DIALLYL TRISULFIDE IN GARLIC (ALLIUM SATIVUM L.) USING GAS CHROMATOGRAPHY
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2020.v12s1.ff035
Abstract: Objective: The purpose of this research was to optimize and validate a method for measuring the levels of diallyl disulfide (DADS) and diallyl trisulfide(DATS) in garlic and single clove garlic.Methods: The analysis was performed using… read more here.
Keywords: diallyl trisulfide; diallyl; gas chromatography; analysis ... See more keywords
Garlic diallyl disulfide and diallyl trisulfide mitigates effects of pro-oxidant induced cellular stress and has immune modulatory function in LPS-stimulated porcine epithelial cells.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of animal science"
DOI: 10.2527/jas2017.1546
Abstract: The objective of the current study was to determine if garlic-derived diallyl disulfide (DADS) and diallyl trisulfide (DATS) could mitigate oxidative and endotoxin stress, using an intestinal porcine epithelial cell (IPEC-J2) model. The experiment was… read more here.
Keywords: diallyl trisulfide; pro oxidant; hydrogen peroxide; dads dats ... See more keywords
Diallyl Disulfide (DADS) Ameliorates Intestinal Candida albicans Infection by Modulating the Gut microbiota and Metabolites and Providing Intestinal Protection in Mice
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.743454
Abstract: Diallyl disulfide (DADS), a garlic extract also known as allicin, has been reported to have numerous biological activities, including anticancer, antifungal, and inflammation-inhibiting activities, among others. Although many studies have assessed whether DADS can treat… read more here.
Keywords: gut microbiota; mice; albicans infection; diallyl disulfide ... See more keywords
Diallyl Disulfide: A Bioactive Garlic Compound with Anticancer Potential
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.943967
Abstract: Cancer is a life-threatening disease caused by the uncontrolled division of cells, which culminates in a solid mass of cells known as a tumor or liquid cancer. It is the leading cause of mortality worldwide,… read more here.
Keywords: garlic compound; bioactive garlic; diallyl disulfide; disulfide bioactive ... See more keywords
Cytotoxic Effects of Nanoliposomal Cisplatin and Diallyl Disulfide on Breast Cancer and Lung Cancer Cell Lines
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041021
Abstract: Dual drug delivery has become the choice of interest nowadays due to its increased therapeutic efficacy in targeting the tumor site precisely. As quoted in recent literature, it has been known to treat several cancers… read more here.
Keywords: cell; diallyl disulfide; cddp; cell lines ... See more keywords
The Effect of Liposomal Diallyl Disulfide and Oxaliplatin on Proliferation of Colorectal Cancer Cells: In Vitro and In Silico Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14020236
Abstract: Diallyl disulfide (DADS) is one of the main bioactive organosulfur compounds of garlic, and its potential against various cancer models has been demonstrated. The poor solubility of DADS in aqueous solutions limits its uses in… read more here.
Keywords: colorectal cancer; cancer cells; diallyl disulfide; cancer ... See more keywords
Diallyl Disulfide Induces Chemosensitization to Sorafenib, Autophagy, and Cell Cycle Arrest and Inhibits Invasion in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122582
Abstract: Hepatocellular carcinoma is the seventh most common type of cancer in the world, with limited treatment options. A promising strategy to treat cancer is to associate chemotherapeutics and plant bioactive compounds. Here, we examined whether… read more here.
Keywords: cell; hepatocellular carcinoma; diallyl disulfide; expression ... See more keywords
Identification of potential targets for differentiation in human leukemia cells induced by diallyl disulfide.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of oncology"
DOI: 10.3892/ijo.2017.3839
Abstract: Diallyl disulfide (DADS) is a primary component of garlic, which has chemopreventive potential. We previously found that moderate doses (15-120 µM) of DADS induced apoptosis and G2/M phase cell cycle arrest. In this study, we observed… read more here.
Keywords: dads induced; leukemia cells; human leukemia; differentiation ... See more keywords