Articles with "diallyl trisulfide" as a keyword



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Diallyl trisulfide plays an antifibrotic role by inhibiting the expression of Bcl‐2 in hepatic stellate cells

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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23097

Abstract: Hepatic fibrosis is an important early stage in the evolution of liver cirrhosis, and specific medicine and therapeutic measures are unavailable to date. Hepatic stellate cells (HSCs) are the main cells involved in the formation… read more here.

Keywords: stellate cells; hepatic fibrosis; hepatic stellate; fibrosis ... See more keywords
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A possible mechanism of inhibition of U87MG and SH-SY5Y cancer cell proliferation by diallyl trisulfide and other aspects of its activity

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Published in 2017 at "Amino Acids"

DOI: 10.1007/s00726-017-2484-4

Abstract: The study was conducted to elucidate the mechanism of antiproliferative and antioxidative action of diallyl trisulfide (DATS), a garlic-derived organosulfur compound. Changes in the l-cysteine desulfuration, and the levels of cystathionine and non-protein thiols in… read more here.

Keywords: diallyl trisulfide; diallyl; mechanism; inhibition ... See more keywords
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The cardioprotective effects of diallyl trisulfide on diabetic rats with ex vivo induced ischemia/reperfusion injury

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Published in 2019 at "Molecular and Cellular Biochemistry"

DOI: 10.1007/s11010-019-03577-w

Abstract: Diallyl trisulfide (DATS) is distinguished as the most potent polysulfide isolated from garlic. The aim of our study was to investigate effects of oral administration of DATS on healthy and diabetic rats, with special attention… read more here.

Keywords: diallyl trisulfide; cardioprotective effects; vivo induced; reperfusion ... See more keywords

Diallyl trisulfide attenuated n-hexane induced neurotoxicity in rats by modulating P450 enzymes.

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Published in 2017 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2017.01.013

Abstract: Chronic exposure to n-hexane can induce serious nerve system impairments without effective preventive medicines. Diallyl trisulfide (DATS) is a garlic-derived organosulfur compound, which has been demonstrated to have many beneficial effects. The current study was… read more here.

Keywords: diallyl trisulfide; hexane; neurotoxicity rats; induced neurotoxicity ... See more keywords
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Codelivery of Epigallocatechin-3-Gallate and Diallyl Trisulfide by Near-Infrared Light-Responsive Mesoporous Polydopamine Nanoparticles for Enhanced Antitumor Efficacy.

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Published in 2020 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2020.120020

Abstract: Green tea extract epigallocatechin-3-gallate (EGCG), as a kind of natural active compounds, has become a research hotspot in cancer treatment. However, poor stability, low bioavailability and antitumor efficacy limit the application of EGCG. In this… read more here.

Keywords: diallyl trisulfide; near infrared; antitumor efficacy; epigallocatechin gallate ... See more keywords
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Preventive effect of Diallyl Trisulfide on cutaneous toxicities induced by EGFR inhibitor

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Published in 2019 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2019.01.023

Abstract: &NA; Cutaneous toxicities are the commonest side effects in patients with cancer treated using epidermal growth factor receptor inhibitors such as erlotinib. For patients with such toxicities, there is a lack of safe, effective pharmacological… read more here.

Keywords: diallyl trisulfide; group; skin; effect diallyl ... See more keywords
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Hepatoprotective effect of diallyl trisulfide against lipopolysaccharide and D-galactosamine induced acute liver failure in mice via suppressing inflammation and apoptosis.

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Published in 2022 at "Toxicology research"

DOI: 10.1093/toxres/tfac005

Abstract: Acute liver failure (ALF), characterized by the quick occurrence of disorder in liver, is a serious liver injury with extremely high mortality. Therefore, we investigated whether diallyl trisulfide (DATS), a natural product from garlic, protected… read more here.

Keywords: liver failure; acute liver; lps gal; mice ... See more keywords
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Can diallyl trisulfide, a dietary garlic-derived compound, activate ferroptosis to overcome therapy resistance in prostate cancer?

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Published in 2021 at "Nutrition and health"

DOI: 10.1177/02601060211018360

Abstract: BACKGROUND Therapy resistance is the underlying reason for poor outcome in prostate cancer (PCa) patients. Diallyl trisulfide (DATS) is an organosulfur compound present in garlic. DATS has been shown to target PCa cells by induction… read more here.

Keywords: diallyl trisulfide; prostate cancer; ferroptosis; resistance ... See more keywords
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VALIDATION AND ANALYSIS OF DIALLYL DISULFIDE AND DIALLYL TRISULFIDE IN GARLIC (ALLIUM SATIVUM L.) USING GAS CHROMATOGRAPHY

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Published in 2020 at "International Journal of Applied Pharmaceutics"

DOI: 10.22159/ijap.2020.v12s1.ff035

Abstract: Objective: The purpose of this research was to optimize and validate a method for measuring the levels of diallyl disulfide (DADS) and diallyl trisulfide(DATS) in garlic and single clove garlic.Methods: The analysis was performed using… read more here.

Keywords: diallyl trisulfide; diallyl; gas chromatography; analysis ... See more keywords
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Garlic diallyl disulfide and diallyl trisulfide mitigates effects of pro-oxidant induced cellular stress and has immune modulatory function in LPS-stimulated porcine epithelial cells.

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Published in 2017 at "Journal of animal science"

DOI: 10.2527/jas2017.1546

Abstract: The objective of the current study was to determine if garlic-derived diallyl disulfide (DADS) and diallyl trisulfide (DATS) could mitigate oxidative and endotoxin stress, using an intestinal porcine epithelial cell (IPEC-J2) model. The experiment was… read more here.

Keywords: diallyl trisulfide; pro oxidant; hydrogen peroxide; dads dats ... See more keywords
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Antimicrobial Effect and the Mechanism of Diallyl Trisulfide against Campylobacter jejuni

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Published in 2021 at "Antibiotics"

DOI: 10.3390/antibiotics10030246

Abstract: Campylobacter jejuni is an important foodborne pathogen causing campylobacteriosis. It can infect humans through the consumption of contaminated chicken products or via the direct handling of animals. Diallyl trisulfide (DATS) is a trisulfide compound from… read more here.

Keywords: jejuni; antimicrobial effect; diallyl trisulfide; campylobacter jejuni ... See more keywords