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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23097
Abstract: Hepatic fibrosis is an important early stage in the evolution of liver cirrhosis, and specific medicine and therapeutic measures are unavailable to date. Hepatic stellate cells (HSCs) are the main cells involved in the formation…
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Keywords:
stellate cells;
hepatic fibrosis;
hepatic stellate;
fibrosis ... See more keywords
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1
Published in 2017 at "Amino Acids"
DOI: 10.1007/s00726-017-2484-4
Abstract: The study was conducted to elucidate the mechanism of antiproliferative and antioxidative action of diallyl trisulfide (DATS), a garlic-derived organosulfur compound. Changes in the l-cysteine desulfuration, and the levels of cystathionine and non-protein thiols in…
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Keywords:
diallyl trisulfide;
diallyl;
mechanism;
inhibition ... See more keywords
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Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03577-w
Abstract: Diallyl trisulfide (DATS) is distinguished as the most potent polysulfide isolated from garlic. The aim of our study was to investigate effects of oral administration of DATS on healthy and diabetic rats, with special attention…
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Keywords:
diallyl trisulfide;
cardioprotective effects;
vivo induced;
reperfusion ... See more keywords
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Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2017.01.013
Abstract: Chronic exposure to n-hexane can induce serious nerve system impairments without effective preventive medicines. Diallyl trisulfide (DATS) is a garlic-derived organosulfur compound, which has been demonstrated to have many beneficial effects. The current study was…
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Keywords:
diallyl trisulfide;
hexane;
neurotoxicity rats;
induced neurotoxicity ... See more keywords
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Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.120020
Abstract: Green tea extract epigallocatechin-3-gallate (EGCG), as a kind of natural active compounds, has become a research hotspot in cancer treatment. However, poor stability, low bioavailability and antitumor efficacy limit the application of EGCG. In this…
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Keywords:
diallyl trisulfide;
near infrared;
antitumor efficacy;
epigallocatechin gallate ... See more keywords
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Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.01.023
Abstract: &NA; Cutaneous toxicities are the commonest side effects in patients with cancer treated using epidermal growth factor receptor inhibitors such as erlotinib. For patients with such toxicities, there is a lack of safe, effective pharmacological…
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Keywords:
diallyl trisulfide;
group;
skin;
effect diallyl ... See more keywords
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Published in 2022 at "Toxicology research"
DOI: 10.1093/toxres/tfac005
Abstract: Acute liver failure (ALF), characterized by the quick occurrence of disorder in liver, is a serious liver injury with extremely high mortality. Therefore, we investigated whether diallyl trisulfide (DATS), a natural product from garlic, protected…
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Keywords:
liver failure;
acute liver;
lps gal;
mice ... See more keywords
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Published in 2021 at "Nutrition and health"
DOI: 10.1177/02601060211018360
Abstract: BACKGROUND Therapy resistance is the underlying reason for poor outcome in prostate cancer (PCa) patients. Diallyl trisulfide (DATS) is an organosulfur compound present in garlic. DATS has been shown to target PCa cells by induction…
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Keywords:
diallyl trisulfide;
prostate cancer;
ferroptosis;
resistance ... See more keywords
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Published in 2020 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2020.v12s1.ff035
Abstract: Objective: The purpose of this research was to optimize and validate a method for measuring the levels of diallyl disulfide (DADS) and diallyl trisulfide(DATS) in garlic and single clove garlic.Methods: The analysis was performed using…
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Keywords:
diallyl trisulfide;
diallyl;
gas chromatography;
analysis ... See more keywords
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Published in 2017 at "Journal of animal science"
DOI: 10.2527/jas2017.1546
Abstract: The objective of the current study was to determine if garlic-derived diallyl disulfide (DADS) and diallyl trisulfide (DATS) could mitigate oxidative and endotoxin stress, using an intestinal porcine epithelial cell (IPEC-J2) model. The experiment was…
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Keywords:
diallyl trisulfide;
pro oxidant;
hydrogen peroxide;
dads dats ... See more keywords
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Published in 2021 at "Antibiotics"
DOI: 10.3390/antibiotics10030246
Abstract: Campylobacter jejuni is an important foodborne pathogen causing campylobacteriosis. It can infect humans through the consumption of contaminated chicken products or via the direct handling of animals. Diallyl trisulfide (DATS) is a trisulfide compound from…
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Keywords:
jejuni;
antimicrobial effect;
diallyl trisulfide;
campylobacter jejuni ... See more keywords