Anti-Inflammatory Effect of Dialyzable Leukocyte Extract in Autoimmune Prostatitis: Evaluation in Animal Model
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DOI: 10.1155/2017/1832853
Abstract: Objective. To evaluate the anti-inflammatory properties of Dialyzable Leukocyte Extract (DLE) in a murine model of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods. Histopathological characterization, prostatein Enzyme-Linked Immunosorbent Assay, and immunohistochemical analysis for CD45, TNF-α,… read more here.
Keywords: anti inflammatory; dialyzable leukocyte; leukocyte extract; autoimmune prostatitis ... See more keywords
Dialyzable Leukocyte Extract (Transferon™) Administration in Sepsis: Experience from a Single Referral Pediatric Intensive Care Unit
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DOI: 10.1155/2019/8980506
Abstract: Immunomodulatory agents have been proposed as therapeutic candidates to improve outcomes in sepsis. Transferon™, a dialyzable leukocyte extract (DLE), has been supported in Mexico as an immunomodulatory adjuvant in anti-infectious therapy. Here we present a… read more here.
Keywords: sepsis; administration; referral pediatric; dialyzable leukocyte ... See more keywords
Validation of a Cell Proliferation Assay to Assess the Potency of a Dialyzable Leukocyte Extract Intended for Batch Release
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DOI: 10.3390/molecules24193426
Abstract: Transferon® is a blood product with immunomodulatory properties constituted by a complex mixture of peptides obtained from a human dialyzable leukocyte extract (DLE). Due to its complex nature, it is necessary to demonstrate batch consistency… read more here.
Keywords: potency; dialyzable leukocyte; cell proliferation; proliferation ... See more keywords