A new class of diamide scaffold: Design, synthesis and biological evaluation as potent antimitotic agents, tubulin polymerization inhibition and apoptosis inducing activity studies.
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DOI: 10.1016/j.bioorg.2018.12.007
Abstract: A new series of diamide functional compounds has been designed, synthesized and confirmed by spectroscopic methods and elemental analyses. All the synthesized compounds were evaluated for their antiproliferative activity on HepG2 cell line. Compounds 3k… read more here.
Keywords: new class; apoptosis; class diamide; potent ... See more keywords