One-Pot Aminoalkylation of Aldehydes: Diastereoselective Synthesis of Vicinal Diamines with Azaarylmethylamines.
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DOI: 10.1021/acs.orglett.9b03287
Abstract: A one-pot synthesis of vicinal diamines with azaarylmethylamines and aldehydes is reported. A diverse array of vicinal diamines could be achieved in up to 92% yield with good to excellent diastereoselectivities (up to 20:1). The… read more here.
Keywords: synthesis vicinal; diamines azaarylmethylamines; vicinal diamines; one pot ... See more keywords