Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.
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DOI: 10.1016/j.immuni.2020.02.006
Abstract: Intrinsic complement C3 activity is integral to human T helper type 1 (Th1) and cytotoxic TÂ cell responses. Increased or decreased intracellular C3 results in autoimmunity and infections, respectively. The mechanisms regulating intracellular C3 expression remain… read more here.
Keywords: lfa; intrinsic complement; complement; expression ... See more keywords