A Coupled Ketoreductase‐Diaphorase Assay for the Detection of Polyethylene Terephthalate‐Hydrolyzing Activity
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DOI: 10.1002/cssc.202102750
Abstract: Abstract In the last two decades, several PET‐degrading enzymes from already known microorganisms or metagenomic sources have been discovered to face the growing environmental concern of polyethylene terephthalate (PET) accumulation. However, there is a limited… read more here.
Keywords: polyethylene terephthalate; activity; diaphorase; hydrolyzing activity ... See more keywords
On the Role of DT-Diaphorase Inhibition in Aminochrome-Induced Neurotoxicity In Vivo
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DOI: 10.1007/s12640-017-9719-8
Abstract: Dopamine oxidation in the pathway leading to neuromelanin formation generates the ortho-quinone aminochrome, which is potentially neurotoxic but normally rapidly converted by DT-diaphorase to nontoxic leukoaminochrome. However, when administered exogenously into rat striatum, aminochrome is… read more here.
Keywords: diaphorase inhibition; role diaphorase; aminochrome; neurotoxicity ... See more keywords
NADPH diaphorase detects S-nitrosylated proteins in aldehyde-treated biological tissues
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DOI: 10.1038/s41598-020-78107-6
Abstract: NADPH diaphorase is used as a histochemical marker of nitric oxide synthase (NOS) in aldehyde-treated tissues. It is thought that the catalytic activity of NOS promotes NADPH-dependent reduction of nitro-blue tetrazolium (NBT) to diformazan. However,… read more here.
Keywords: reduction; nadph dependent; aldehyde treated; diformazan ... See more keywords
UDP-glucose dehydrogenase (UGDH) activity is suppressed by peroxide and promoted by PDGF in fibroblast-like synoviocytes: Evidence of a redox control mechanism
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DOI: 10.1371/journal.pone.0274420
Abstract: UDP-glucose dehydrogenase (UGDH) generates essential precursors of hyaluronic acid (HA) synthesis, however mechanisms regulating its activity are unclear. We used enzyme histostaining and quantitative image analysis to test whether cytokines that stimulate HA synthesis upregulate… read more here.
Keywords: ugdh activity; udp glucose; diaphorase; dehydrogenase ugdh ... See more keywords