Visible-light-promoted synthesis of diaryl sulfides under air
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.06.006
Abstract: Abstract A convergent, organocatalytic visible-light-mediated process for the synthesis of diaryl sulfides has been developed. A broad range of aryl thiols reacted with various aryl diazonium salts in the presence of eosin Y under air… read more here.
Keywords: synthesis diaryl; diaryl sulfides; visible light; air ... See more keywords
Ultrasound assisted one-pot synthesis of 1,2-diaryl azaindoles via Pd/C-Cu catalysis: Identification of potential cytotoxic agents
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.151326
Abstract: Abstract Ultrasound assisted one-pot and direct access to 1,2-diaryl substituted azaindole derivatives has been achieved via the sequential N-arylation followed by coupling-cyclization under Pd/C-Cu catalysis. The methodology involved initial C N bond forming reaction (step… read more here.
Keywords: pot; catalysis; assisted one; diaryl ... See more keywords
Metal-Free Diaryl Etherification of Tertiary Amines by Ortho-C(sp2)-H Functionalization for Synthesis of Dibenzoxazepines and -ones.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03328
Abstract: A phenyliodine(III) diacetate mediated umpolung reactivity of the tertiary amines with suitably substituted o-hydroxybenzyl and phenyl groups is exploited to facilitate o-C(sp2)-H functionalization to afford diaryl ethers. The presence of an o-CHO and secondary amine… read more here.
Keywords: diaryl; sp2 functionalization; tertiary amines; synthesis dibenzoxazepines ... See more keywords
Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with In Vitro Growth Inhibitory and In Vivo Antitumor Activity
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03405
Abstract: The vicinal diaryl heterocyclic framework has been widely used for the development of compounds with significant bioactivities. In this study, a series of diaryl heterocycles were designed and synthesized based on an in-house diaryl isoxazole… read more here.
Keywords: antitumor; antitumor activity; vicinal diaryl; diaryl substituted ... See more keywords
Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b08640
Abstract: Diaryl ketones are important building blocks for synthesizing pharmaceuticals and are generally regarded as "difficult-to-reduce" ketones due to the large steric hindrance of their two bulky aromatic side chains. Alcohol dehydrogenase from Kluyveromyces polyspora (… read more here.
Keywords: inversion; polar gate; diaryl; alcohol dehydrogenase ... See more keywords
A11, a novel diaryl acylhydrazone derivative, exerts neuroprotection against ischemic injury in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-018-0028-4
Abstract: There is an urgent need to develop effective therapies for ischemic stroke, but the complicated pathological processes after ischemia make doing so difficult. In the current study, we identified a novel diaryl acylhydrazone derivative, A11,… read more here.
Keywords: novel diaryl; ischemic stroke; diaryl; diaryl acylhydrazone ... See more keywords
Binary interpnictogen compounds bearing diaryl bismuth fragments bound to all lighter pnictogens.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt00472k
Abstract: Multiple interpnictogen compounds with covalent single bonds between a diarylbismuth fragment and all lighter pnictogens were prepared from the corresponding diarylhalido bismuthanes. The aminobismuthanes Ph2BiNMe2 (1) and Mes2BiNMe2 (2) (Mes = 2,4,6-trimethylphenyl-) have been obtained… read more here.
Keywords: lighter pnictogens; reaction; interpnictogen compounds; diaryl ... See more keywords
Enantioselective synthesis of α-tetrasubstituted (3-indolizinyl) (diaryl)methanamines via chiral phosphoric acid catalysis
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra03750e
Abstract: An enantioselective Friedel–Crafts reaction of cyclic α-diaryl N-acyl imines with indolizines catalyzed by a chiral spirocyclic phosphoric acid has been developed. The asymmetric transformation proceeds smoothly to afford α-tetrasubstituted (3-indolizinyl) (diaryl)methanamines in good yields with… read more here.
Keywords: indolizinyl diaryl; phosphoric acid; diaryl; diaryl methanamines ... See more keywords
A cross-conjugation approach for high-performance diaryl-hemithioindigo photoswitches
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d2sc06939c
Abstract: Diaryl-hemithioindigos (diaryl-HTIs) are derivatives of a novel class of highly functionalized indigoid chromophores. In this work a systematic study of the electronic effects on their photoswitching reveals the design principles for achieving an excellent property… read more here.
Keywords: conjugation approach; performance; diaryl htis; diaryl ... See more keywords
C–S Bond Alkynylation of Diaryl Sulfoxides with Terminal Alkynes by Means of a Palladium–NHC Catalyst
Sign Up to like & getrecommendations! Published in 2017 at "Synlett"
DOI: 10.1055/s-0036-1591676
Abstract: Sonogashira–Hagihara-type alkynylation of diaryl sulfoxides with unactivated terminal alkynes has been developed. With a combination of a palladium–NHC catalyst and LiOtBu as a base, a series of diaryl sulfoxides were converted into the alkynylated products… read more here.
Keywords: palladium nhc; diaryl sulfoxides; terminal alkynes; diaryl ... See more keywords
Synthesis and dynamic NMR studies of novel hydantoin and thiohydantoin derivatives. Crystal structure of diethyl 2-(4,4-diaryl-2,5-dioxoimidazolidin-1-yl) fumarate and diethyl 2-(4,4-diaryl-2-mercapto-5-oxo-4,5-dihydro-1H-imidazol-1-yl)fumarate
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Chemical Research"
DOI: 10.3184/174751917x14932244903881
Abstract: The reaction of stoichiometric amounts of dialkyl acetylenedicarboxylates with triphenylphosphine in the presence of hydantoins or thiohydantoins afforded stable crystalline phosphorus ylides. These compounds undergo smooth elimination of PPh3 to produce dialkyl 2-(4,4-diaryl-2,5-dioxoimidazolidin-1-yl)fumarate, 4 or… read more here.
Keywords: dioxoimidazolidin fumarate; diaryl dioxoimidazolidin; diaryl; diethyl diaryl ... See more keywords